Literature DB >> 23197295

Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase.

A Degterev, J L Maki, J Yuan.   

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Year:  2012        PMID： 23197295      PMCID： PMC3554332          DOI： 10.1038/cdd.2012.133

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN： 1350-9047            Impact factor:   15.828


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  6 in total

1.  Structure-activity relationship study of novel necroptosis inhibitors.

Authors:  Xin Teng; Alexei Degterev; Prakash Jagtap; Xuechao Xing; Sungwoon Choi; Régine Denu; Junying Yuan; Gregory D Cuny
Journal:  Bioorg Med Chem Lett       Date:  2005-11-15       Impact factor: 2.823

2.  Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.

Authors:  Alexei Degterev; Zhihong Huang; Michael Boyce; Yaqiao Li; Prakash Jagtap; Noboru Mizushima; Gregory D Cuny; Timothy J Mitchison; Michael A Moskowitz; Junying Yuan
Journal:  Nat Chem Biol       Date:  2005-05-29       Impact factor: 15.040

3.  Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

Authors:  Alexander J Muller; James B DuHadaway; P Scott Donover; Erika Sutanto-Ward; George C Prendergast
Journal:  Nat Med       Date:  2005-02-13       Impact factor: 53.440

Review 4.  Programmed necrosis from molecules to health and disease.

Authors:  Lorenzo Galluzzi; Tom Vanden Berghe; Nele Vanlangenakker; Sabrina Buettner; Tobias Eisenberg; Peter Vandenabeele; Frank Madeo; Guido Kroemer
Journal:  Int Rev Cell Mol Biol       Date:  2011       Impact factor: 6.813

5.  Identification of RIP1 kinase as a specific cellular target of necrostatins.

Authors:  Alexei Degterev; Junichi Hitomi; Megan Germscheid; Irene L Ch'en; Olga Korkina; Xin Teng; Derek Abbott; Gregory D Cuny; Chengye Yuan; Gerhard Wagner; Stephen M Hedrick; Scott A Gerber; Alexey Lugovskoy; Junying Yuan
Journal:  Nat Chem Biol       Date:  2008-05       Impact factor: 15.040

6.  A novel role for RIP1 kinase in mediating TNFα production.

Authors:  D E Christofferson; Y Li; J Hitomi; W Zhou; C Upperman; H Zhu; S A Gerber; S Gygi; J Yuan
Journal:  Cell Death Dis       Date:  2012-06-14       Impact factor: 8.469
  6 in total
  96 in total

1.  Necroptosis inhibition as a therapy for Niemann-Pick disease, type C1: Inhibition of RIP kinases and combination therapy with 2-hydroxypropyl-β-cyclodextrin.

Authors:  A Cougnoux; S Clifford; A Salman; S-L Ng; J Bertin; F D Porter
Journal:  Mol Genet Metab       Date:  2018-10-30       Impact factor: 4.797

Review 2.  Pathophysiology of glia in perinatal white matter injury.

Authors:  Stephen A Back; Paul A Rosenberg
Journal:  Glia       Date:  2014-03-31       Impact factor: 7.452

3.  RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.

Authors:  Malek Najjar; Danish Saleh; Matija Zelic; Shoko Nogusa; Saumil Shah; Albert Tai; Joshua N Finger; Apostolos Polykratis; Peter J Gough; John Bertin; Michael Whalen; Manolis Pasparakis; Siddharth Balachandran; Michelle Kelliher; Alexander Poltorak; Alexei Degterev
Journal:  Immunity       Date:  2016-07-05       Impact factor: 31.745

Review 4.  Photoreceptor cell death and rescue in retinal detachment and degenerations.

Authors:  Yusuke Murakami; Shoji Notomi; Toshio Hisatomi; Toru Nakazawa; Tatsuro Ishibashi; Joan W Miller; Demetrios G Vavvas
Journal:  Prog Retin Eye Res       Date:  2013-08-28       Impact factor: 21.198

5.  Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein.

Authors:  Kota Sato; Songhua Li; William C Gordon; Jibao He; Gregory I Liou; James M Hill; Gabriel H Travis; Nicolas G Bazan; Minghao Jin
Journal:  J Neurosci       Date:  2013-10-30       Impact factor: 6.167

Review 6.  Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

Authors:  Tom Vanden Berghe; Andreas Linkermann; Sandrine Jouan-Lanhouet; Henning Walczak; Peter Vandenabeele
Journal:  Nat Rev Mol Cell Biol       Date:  2014-02       Impact factor: 94.444

Review 7.  Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death.

Authors:  Dimitry Ofengeim; Junying Yuan
Journal:  Nat Rev Mol Cell Biol       Date:  2013-10-16       Impact factor: 94.444

8.  Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner.

Authors:  N Preyat; M Rossi; J Kers; L Chen; J Bertin; P J Gough; A Le Moine; A Rongvaux; F Van Gool; O Leo
Journal:  Cell Death Differ       Date:  2015-05-22       Impact factor: 15.828

Review 9.  Staying alive: cell death in antiviral immunity.

Authors:  Jason W Upton; Francis Ka-Ming Chan
Journal:  Mol Cell       Date:  2014-04-24       Impact factor: 17.970

10.  When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157.

Authors:  Diego Rojas-Rivera; Tinneke Delvaeye; Ria Roelandt; Wim Nerinckx; Koen Augustyns; Peter Vandenabeele; Mathieu J M Bertrand
Journal:  Cell Death Differ       Date:  2017-04-28       Impact factor: 15.828
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