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Literature DB >> 23196059

MicroRNAs as potential biomarkers in human solid tumors.

Abstract

MicroRNAs (miRNAs) regulate the expression of approximately 30% of protein-coding genes. Functions of miRNAs are essential to maintain a steady state of cellular machinery. Dysregulations of miRNAs play pivotal roles in the initiation and progression of malignancies. Abnormal miRNA expressions have been found in a variety of human solid tumors. Furthermore, extracellular miRNAs could circulate in body fluids, and hence show great promise for refining diagnosis and prognosis of cancer. Here we review the progress of analysis of microRNAs as a potential approach for diagnosis and prognosis of solid cancer. We will also discuss obstacles in developing miRNAs as circulating biomarkers.

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Year: 2012 PMID： 23196059 PMCID： PMC3552101 DOI： 10.1016/j.canlet.2012.11.001

Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679

143 in total

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Journal: J Pathol Date: 2010-01 Impact factor: 7.996

2. Extensive modulation of a set of microRNAs in primary glioblastoma.

Authors: S A Ciafrè; S Galardi; A Mangiola; M Ferracin; C-G Liu; G Sabatino; M Negrini; G Maira; C M Croce; M G Farace
Journal: Biochem Biophys Res Commun Date: 2005-09-09 Impact factor: 3.575

3. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis.

Authors: Nozomu Yanaihara; Natasha Caplen; Elise Bowman; Masahiro Seike; Kensuke Kumamoto; Ming Yi; Robert M Stephens; Aikou Okamoto; Jun Yokota; Tadao Tanaka; George Adrian Calin; Chang-Gong Liu; Carlo M Croce; Curtis C Harris
Journal: Cancer Cell Date: 2006-03 Impact factor: 31.743

4. Regulation of p27Kip1 by miRNA 221/222 in glioblastoma.

Authors: Jana K Gillies; Ian A J Lorimer
Journal: Cell Cycle Date: 2007-05-31 Impact factor: 4.534

5. Normalization of microRNA expression levels in quantitative RT-PCR assays: identification of suitable reference RNA targets in normal and cancerous human solid tissues.

Authors: Heidi J Peltier; Gary J Latham
Journal: RNA Date: 2008-03-28 Impact factor: 4.942

6. Suppression of non-small cell lung tumor development by the let-7 microRNA family.

Authors: Madhu S Kumar; Stefan J Erkeland; Ryan E Pester; Cindy Y Chen; Margaret S Ebert; Phillip A Sharp; Tyler Jacks
Journal: Proc Natl Acad Sci U S A Date: 2008-02-28 Impact factor: 11.205

7. Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma.

Authors: Johannes H Schulte; Tobias Marschall; Marcel Martin; Philipp Rosenstiel; Pieter Mestdagh; Stefanie Schlierf; Theresa Thor; Jo Vandesompele; Angelika Eggert; Stefan Schreiber; Sven Rahmann; Alexander Schramm
Journal: Nucleic Acids Res Date: 2010-05-13 Impact factor: 16.971

8. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins.

Authors: Kasey C Vickers; Brian T Palmisano; Bassem M Shoucri; Robert D Shamburek; Alan T Remaley
Journal: Nat Cell Biol Date: 2011-03-20 Impact factor: 28.824

9. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries.

Authors: Stacia K Wyman; Rachael K Parkin; Patrick S Mitchell; Brian R Fritz; Kathy O'Briant; Andrew K Godwin; Nicole Urban; Charles W Drescher; Beatrice S Knudsen; Muneesh Tewari
Journal: PLoS One Date: 2009-04-23 Impact factor: 3.240

10. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.

Authors: Joachim Silber; Daniel A Lim; Claudia Petritsch; Anders I Persson; Alika K Maunakea; Mamie Yu; Scott R Vandenberg; David G Ginzinger; C David James; Joseph F Costello; Gabriele Bergers; William A Weiss; Arturo Alvarez-Buylla; J Graeme Hodgson
Journal: BMC Med Date: 2008-06-24 Impact factor: 8.775

99 in total

1. Prognostic value of circulating microRNA-21 in digestive system cancers: a meta-analysis.

Authors: Ting-Ting Ye; Yin-Long Yang; Xin-Ying Liu; Qian-Qing Ji; Yi-Fei Pan; You-Qun Xiang
Journal: Int J Clin Exp Med Date: 2014-04-15

2. Hemolysis-free plasma miR-214 as novel biomarker of gastric cancer and is correlated with distant metastasis.

Authors: Ke-Cheng Zhang; Hong-Qing Xi; Jian-Xin Cui; Wei-Song Shen; Ji-Yang Li; Bo Wei; Lin Chen
Journal: Am J Cancer Res Date: 2015-01-15 Impact factor: 6.166

3. Digital PCR quantification of miRNAs in sputum for diagnosis of lung cancer.

Authors: Ning Li; Jie Ma; Maria A Guarnera; HongBin Fang; Ling Cai; Feng Jiang
Journal: J Cancer Res Clin Oncol Date: 2013-11-27 Impact factor: 4.553

4. Prognostic significance of microRNA-16 expression in human colorectal cancer.

Authors: Jun Qian; Bin Jiang; Min Li; Juan Chen; Mingzhi Fang
Journal: World J Surg Date: 2013-12 Impact factor: 3.352

5. Bioinformatic and metabolomic analysis reveals miR-155 regulates thiamine level in breast cancer.

Authors: Sinae Kim; Je-keun Rhee; Hyun Ju Yoo; Hee Jin Lee; Eun Ji Lee; Jong Won Lee; Jong Han Yu; Byung Ho Son; Gyungyup Gong; Sung Bae Kim; Shree Ram Singh; Sei Hyun Ahn; Suhwan Chang
Journal: Cancer Lett Date: 2014-12-04 Impact factor: 8.679

6. Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes.

Authors: Alyssa Charrier; Ruju Chen; Li Chen; Sherri Kemper; Takako Hattori; Masaharu Takigawa; David R Brigstock
Journal: J Cell Commun Signal Date: 2014-01-26 Impact factor: 5.782