| Literature DB >> 23195761 |
M M de Souza1, R A de Jesus, V Cechinel-Filho, V Schlemper.
Abstract
Marrubium vulgare L. is a medicinal plant used in folk medicine to cure a variety of diseases. Recently we have demonstrated that a hydroalcoholic extract of this plant showed significant, nonspecific antispasmodic effects on isolated smooth muscle. In this report, we have investigated the possible analgesic effects of the same hydroalcoholic extract in different models of pain in mice. The results suggest that this extract exhibits significant analgesic activity, antagonizing chemically-induced acute pain. Such effects may be related to the presence of steroids and terpenes, which were detected by TLC analysis.Entities:
Year: 1998 PMID: 23195761 DOI: 10.1016/S0944-7113(98)80005-6
Source DB: PubMed Journal: Phytomedicine ISSN: 0944-7113 Impact factor: 5.340