Literature DB >> 23195311

Accessing and mining data from large-scale mouse phenotyping projects.

Hugh Morgan1, Michelle Simon, Ann-Marie Mallon.   

Abstract

Comprehensive phenotyping through the International Mouse Phenotyping Consortium (IMPC)-www.mousephenotype.org-will reveal the pleiotropic functions of every gene in the mouse genome and uncover the wider role of genetic loci within diverse biological systems. The informatics challenge will be to develop an infrastructure to acquire the diverse and complex data sets generated from broad-based phenotyping and disseminate these data in an integrated manner to the scientific community. We describe here the current methodologies implemented to capture and disseminate these data, and plans within the Knockout Mouse Phenotyping Project (KOMP2) (http://commonfund.nih.gov/KOMP2/)-funded informatics consortium to scale these implementations to manage the surge in data from the IMPC.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Mesh：

Year:  2012        PMID： 23195311     DOI： 10.1016/B978-0-12-398323-7.00003-3

Source DB:  PubMed          Journal:  Int Rev Neurobiol        ISSN： 0074-7742            Impact factor:   3.230


  5 in total

1.  Linking tissues to phenotypes using gene expression profiles.

Authors:  Anika Oellrich; Damian Smedley
Journal:  Database (Oxford)       Date:  2014-03-13       Impact factor: 3.451

2.  Identification of genes required for eye development by high-throughput screening of mouse knockouts.

Authors:  Bret A Moore; Brian C Leonard; Lionel Sebbag; Sydney G Edwards; Ann Cooper; Denise M Imai; Ewan Straiton; Luis Santos; Christopher Reilly; Stephen M Griffey; Lynette Bower; David Clary; Jeremy Mason; Michel J Roux; Hamid Meziane; Yann Herault; Colin McKerlie; Ann M Flenniken; Lauryl M J Nutter; Zorana Berberovic; Celeste Owen; Susan Newbigging; Hibret Adissu; Mohammed Eskandarian; Chih-Wei Hsu; Sowmya Kalaga; Uchechukwu Udensi; Chinwe Asomugha; Ritu Bohat; Juan J Gallegos; John R Seavitt; Jason D Heaney; Arthur L Beaudet; Mary E Dickinson; Monica J Justice; Vivek Philip; Vivek Kumar; Karen L Svenson; Robert E Braun; Sara Wells; Heather Cater; Michelle Stewart; Sharon Clementson-Mobbs; Russell Joynson; Xiang Gao; Tomohiro Suzuki; Shigeharu Wakana; Damian Smedley; J K Seong; Glauco Tocchini-Valentini; Mark Moore; Colin Fletcher; Natasha Karp; Ramiro Ramirez-Solis; Jacqueline K White; Martin Hrabe de Angelis; Wolfgang Wurst; Sara M Thomasy; Paul Flicek; Helen Parkinson; Steve D M Brown; Terrence F Meehan; Patsy M Nishina; Stephen A Murray; Mark P Krebs; Ann-Marie Mallon; K C Kent Lloyd; Christopher J Murphy; Ala Moshiri
Journal:  Commun Biol       Date:  2018-12-21

Review 3.  Evolution of Complexity. Molecular Aspects of Preassembly.

Authors:  Fredric M Menger; Syed A A Rizvi
Journal:  Molecules       Date:  2021-10-31       Impact factor: 4.411

4.  Publishing and sharing multi-dimensional image data with OMERO.

Authors:  Jean-Marie Burel; Sébastien Besson; Colin Blackburn; Mark Carroll; Richard K Ferguson; Helen Flynn; Kenneth Gillen; Roger Leigh; Simon Li; Dominik Lindner; Melissa Linkert; William J Moore; Balaji Ramalingam; Emil Rozbicki; Aleksandra Tarkowska; Petr Walczysko; Chris Allan; Josh Moore; Jason R Swedlow
Journal:  Mamm Genome       Date:  2015-07-30       Impact factor: 2.957

Review 5.  Phenotype ontologies and cross-species analysis for translational research.

Authors:  Peter N Robinson; Caleb Webber
Journal:  PLoS Genet       Date:  2014-04-03       Impact factor: 5.917
  5 in total

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