Literature DB >> 23194972

Antispasmodic effects of hydroalcoholic extract of Marrubium vulgare on isolated tissues.

V Schlemper1, A Ribas, M Nicolau, V Cechinel Filho.   

Abstract

Marrubium vulgare is a medicinal plant used in Brazil and in many countries in folk medicine against several diseases, including gastrointestinal disorders. In this study, we have evaluated the effects of hydroalcoholic extract of the roots and aerial parts of M. vulgare in several smooth muscle preparations in vitro. The results showed that this extract exert a significant antispasmodic activity which inhibits the action of some neurotransmitters, such as acetylcholine, bradykinin, prostaglandin E(2), histamine and oxytocin, with putative selectivity for cholinergic contractions. These findings support the popular use in folk medicine of this plant as an antispasmodic. Copyright © 1996 Gustav Fischer Verlag · Stuttgart · Jena · New York. Published by Elsevier GmbH.. All rights reserved.

Entities:  

Year:  1996        PMID： 23194972     DOI： 10.1016/S0944-7113(96)80038-9

Source DB:  PubMed          Journal:  Phytomedicine        ISSN： 0944-7113            Impact factor:   5.340


  11 in total

1.  Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus.

Authors:  Cassandra L Quave; Lisa R W Plano; Traci Pantuso; Bradley C Bennett
Journal:  J Ethnopharmacol       Date:  2008-05-13       Impact factor: 4.360

2.  Neurobehavioral and Biochemical Evidences in Support of Protective Effect of Marrubiin (Furan Labdane Diterpene) from Marrubium vulgare Linn. and Its Extracts after Traumatic Brain Injury in Experimental Mice.

Authors:  Govind Singh; Rekha Valecha; Govind Shukla; Deepak Kaushik; Mohammad Akhlaquer Rahman; Rupesh K Gautam; Kumud Madan; Vineet Mittal; Rajeev K Singla
Journal:  Evid Based Complement Alternat Med       Date:  2022-05-24       Impact factor: 2.650

3.  Chromatographic Fingerprint Analysis of Marrubiin in Marrubium vulgare L. via HPTLC Technique.

Authors:  Keyvan Yousefi; Sanaz Hamedeyazdan; Mohammadali Torbati; Fatemeh Fathiazad
Journal:  Adv Pharm Bull       Date:  2016-03-17

4.  The in-vitro evaluation of antibacterial, antifungal and cytotoxic properties of Marrubium vulgare L. essential oil grown in Tunisia.

Authors:  Zied Zarai; Adel Kadri; Ines Ben Chobba; Riadh Ben Mansour; Ahmed Bekir; Hafedh Mejdoub; Néji Gharsallah
Journal:  Lipids Health Dis       Date:  2011-09-21       Impact factor: 3.876

5.  Role of the Rosa canina L. leaf extract as an antidiarrheal drug in rodents.

Authors:  Rajesh J Mandade; Avijit Choudhury; Amol Harsulkar; Ravikiran Wakade
Journal:  Indian J Pharmacol       Date:  2011-05       Impact factor: 1.200

6.  Inhibitory Effects of Physalis alkekengi L., Alcea rosea L., Bunium persicum B. Fedtsch. and Marrubium vulgare L. on Mushroom Tyrosinase.

Authors:  Foroogh Namjoyan; Alireza Jahangiri; Mohammad Ebrahim Azemi; Elaheh Arkian; Hamideh Mousavi
Journal:  Jundishapur J Nat Pharm Prod       Date:  2015-02-20

7.  Marrubium vulgare L. methanolic extract inhibits inflammatory response and prevents cardiomyocyte fibrosis in isoproterenol-induced acute myocardial infarction in rats.

Authors:  Keyvan Yousefi; Fatemeh Fathiazad; Hamid Soraya; Maryam Rameshrad; Nasrin Maleki-Dizaji; Alireza Garjani
Journal:  Bioimpacts       Date:  2014-02-27

Review 8.  Natural Antispasmodics: Source, Stereochemical Configuration, and Biological Activity.

Authors:  Edith Fabiola Martínez-Pérez; Zaida N Juárez; Luis R Hernández; Horacio Bach
Journal:  Biomed Res Int       Date:  2018-10-08       Impact factor: 3.411

9.  Spray Drying of a Subcritical Extract Using Marrubium vulgare as a Method of Choice for Obtaining High Quality Powder.

Authors:  Aleksandra Gavarić; Jelena Vladić; Rita Ambrus; Stela Jokić; Piroska Szabó-Révész; Milan Tomić; Marijana Blažić; Senka Vidović
Journal:  Pharmaceutics       Date:  2019-10-11       Impact factor: 6.321

10.  Biochemical profile and in vitro biological activities of extracts from seven folk medicinal plants growing wild in southern Tunisia.

Authors:  Hajer Tlili; Najjaa Hanen; Abdelkerim Ben Arfa; Mohamed Neffati; Abdelbasset Boubakri; Daniela Buonocore; Maurizia Dossena; Manuela Verri; Enrico Doria
Journal:  PLoS One       Date:  2019-09-17       Impact factor: 3.240
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