Literature DB >> 23190218

Changes and significance of serum angiopoietin-2 levels in patients with coronary heart disease.

Xin Wang1, Huijuan Yong, Lin Mi, Yun Bai, Lijun Guo, Wei Gao, Ming Cui, Yongzhen Zhang.   

Abstract

Coronary heart disease (CHD) is characterized by inflammatory process and endothelial dysfunction. To investigate angiopoietin-2 (Ang-2) profiles, we evaluated serum Ang-2 levels in different types of CHD in 166 subjects. Ang-2 was measured by enzyme-linked immunosorbent assay. Serum Ang-2 levels were significantly elevated in patients with CHD and gradually increased with advance of CHD. Ang-2 was positively correlated with Gensini scores and hs-CRP. Ang-2 might have potential implication in detecting and monitoring the progression of CHD.

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Year:  2012        PMID： 23190218     DOI： 10.3109/1354750X.2012.727028

Source DB:  PubMed          Journal:  Biomarkers        ISSN： 1354-750X            Impact factor:   2.658


  8 in total

1.  Angiopoietin-2 as a biomarker of non-ST-segment elevation myocardial infarction in patients with or without type 2 diabetes.

Authors:  Tomasz Skowerski; Katarzyna Nabrdalik; Hanna Kwiendacz; Maciej Pajak; Katarzyna Mizia-Stec; Zbigniew Gasior; Janusz Gumprecht
Journal:  Arch Med Sci       Date:  2019-11-07       Impact factor: 3.707

2.  Associations of Angiopoietins With Heart Failure Incidence and Severity.

Authors:  Brandon S Peplinski; Brian A Houston; David A Bluemke; Steven M Kawut; Todd M Kolb; Richard A Kronmal; Joao A C Lima; David D Ralph; Samuel G Rayner; Zachary L Steinberg; Ryan J Tedford; Peter J Leary
Journal:  J Card Fail       Date:  2021-04-17       Impact factor: 6.592

3.  Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice.

Authors:  Thomas L Theelen; Jari P Lappalainen; Judith C Sluimer; Erika Gurzeler; Jack P Cleutjens; Marion J Gijbels; Erik A L Biessen; Mat J A P Daemen; Kari Alitalo; Seppo Ylä-Herttuala
Journal:  Atherosclerosis       Date:  2015-06-03       Impact factor: 5.162

4.  Effects of Percutaneous Coronary Intervention on Serum Angiopoietin-2 in Patients with Coronary Heart Disease.

Authors:  Zhi-Yu Zeng; Chun Gui; Lang Li; Xiao-Min Wei
Journal:  Chin Med J (Engl)       Date:  2016-03-20       Impact factor: 2.628

5.  Angiopoietin-2 provides no incremental predictive value for the presence of obstructive coronary artery disease over N-terminal pro-brain natriuretic peptide.

Authors:  Wen Jian; Chang-Hua Mo; Guo-Liang Yang; Lang Li; Chun Gui
Journal:  J Clin Lab Anal       Date:  2019-07-01       Impact factor: 2.352

6.  Role of angiopoietin-2 in the cardioprotective effect of fibroblast growth factor 21 on ischemia/reperfusion-induced injury in H9c2 cardiomyocytes.

Authors:  Shuoqiang Hu; Shujun Cao; Jinghua Liu
Journal:  Exp Ther Med       Date:  2017-06-08       Impact factor: 2.447

7.  Serum angiopoietin-2 concentrations of post-PCI are correlated with the parameters of renal function in patients with coronary artery disease.

Authors:  Wen Jian; Lang Li; Xiao-Min Wei; Jia-Hui Guan; Guo-Liang Yang; Chun Gui
Journal:  Medicine (Baltimore)       Date:  2019-01       Impact factor: 1.889

8.  Prognostic value of angiopoietin-2 for patients with coronary heart disease after elective PCI.

Authors:  Wen Jian; Lang Li; Xiao-Min Wei; Cheng-Qiang Wu; Chun Gui
Journal:  Medicine (Baltimore)       Date:  2019-02       Impact factor: 1.817
  8 in total

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