| Literature DB >> 23190207 |
Andrea Porcheddu1, Manuel G Mura, Lidia De Luca, Marianna Pizzetti, Maurizio Taddei.
Abstract
In a new version of the Fischer indole synthesis, primary and secondary alcohols have been catalytically oxidized in the presence of phenylhydrazines and protic or Lewis acids to give the corresponding indoles. The overall reaction can be accomplished in one step, and the use of alcohols instead of aldehyes or ketones as starting materials has several advantages in terms of a large selection of reagents, easy handling, and safety of the process.Entities:
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Year: 2012 PMID： 23190207 DOI： 10.1021/ol3030956
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005