Literature DB >> 23190032

Benzimidazole derivatives as potential anticancer agents.

Ahmed A El Rashedy1, Hassan Y Aboul-Enein.   

Abstract

Benzimidazole ring system is found in many bioactive heterocyclic compounds because of their diverse biological and clinical applications. Furthermore, benzimidazole derivatives are structural isosters of naturally occurring nucleotides, thus they can interact with biological macromolecules such as proteins, enzymes and receptors. This review discusses the benzimidazole derivatives which possess anticancer activity of medicinal efficacy.

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Year:  2013        PMID： 23190032     DOI： 10.2174/138955713804999847

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  11 in total

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Journal:  Br J Pharmacol       Date:  2019-09-15       Impact factor: 8.739

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4.  Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides.

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5.  Mutagenic Study of Benzimidazole Derivatives with (+S9) and without (-S9) Metabolic Activation.

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6.  Crystal structure and Hirshfeld surface analysis of 4-[4-(1H-benzo[d]imidazol-2-yl)phen-oxy]phthalo-nitrile dimethyl sulfoxide monosolvate.

Authors:  Sibel Demir Kanmazalp; Pınar Şen; Necmi Dege; Salih Zeki Yildiz; Namık Ozdemir; Irina A Golenya
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2019-05-10

Review 7.  Benzotriazole: An overview on its versatile biological behavior.

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Journal:  Materials (Basel)       Date:  2022-03-30       Impact factor: 3.623

Review 9.  β-Carboline-based molecular hybrids as anticancer agents: a brief sketch.

Authors:  Jay Prakash Soni; Yogesh Yeole; Nagula Shankaraiah
Journal:  RSC Med Chem       Date:  2021-03-24

Review 10.  Oxidative dehydrogenation of C-C and C-N bonds: A convenient approach to access diverse (dihydro)heteroaromatic compounds.

Authors:  Santanu Hati; Ulrike Holzgrabe; Subhabrata Sen
Journal:  Beilstein J Org Chem       Date:  2017-08-15       Impact factor: 2.883
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