Literature DB >> 23189554

[Synthesis and anti-tumor properties of myelopeptide MP-1].

L A Fonina, E M Treshchalina, R G Belevskaia, A A Az'muko, M A Efremov, L A Sedakova, E A Kirilina.   

Abstract

We have studied anti-tumor properties of bone marrow derived peptide Phe-Leu-Gly-Phe-Pro-Thr (MP-1) synthesized by classical methods. It was shown that MP-1 enhanced the effect ofcytostatic therapy of lymphatic leukemia P388 and increased latent growth period of P388 tumors implanted in irradiated mice. MP-1 also decreased metastasis of mouse breast adenocarcinoma Ca-755 after surgery.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 23189554     DOI: 10.1134/s1068162012040073

Source DB:  PubMed          Journal:  Bioorg Khim        ISSN: 0132-3423


  1 in total

1.  Regulation of the peritoneal macrophage functional activity by the MP-5 and MP-6 myelopeptides under stress.

Authors:  S V Gein; T V Gavrilova; O N Gein; L S Nikitina; M V Chereshneva; V A Chereshnev; E A Kirilina
Journal:  Dokl Biol Sci       Date:  2017-09-01
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.