PURPOSE: To evaluate whether adding bone substitute materials to autogenous particulated bone (PAB) might have an effect on the density of the grafted bone after maxillary sinus augmentation. MATERIALS AND METHODS:Thirty healthy patients undergoing lateral antrostomy were included. Sinuses were augmented at random with PAB (n=10) (control group); a mixture of PAB and beta-tricalcium phosphate (Β-TCP) (n=10) (experimental group); or a mixture of PAB, Β-TCP, and hydroxyapatite (HA) (n=10) (experimental group). A sample of each graft material was obtained at time of maxillary sinus augmentation, and microcomputed tomography (Μ-CT) analyses were performed. Five months later, samples of the augmented areas (n=23) were harvested by means of a trephine bur, and Μ-CT analyses of these samples were performed. Density values for the bone were compared to the data obtained 5 months before from the original material. RESULTS: All groups showed increasing density values after a healing time of 5 months. Because of a high dropout rate, the sample size was too small to compare the groups statistically. CONCLUSIONS:Bone density increased after maxillary sinus augmentation for both PAB alone or in combination with substitute materials based on HA and/or Β-TCP particles. A larger sample size and a split-mouth design would help to reliably reveal significant differences between the single materials.
RCT Entities:
PURPOSE: To evaluate whether adding bone substitute materials to autogenous particulated bone (PAB) might have an effect on the density of the grafted bone after maxillary sinus augmentation. MATERIALS AND METHODS: Thirty healthy patients undergoing lateral antrostomy were included. Sinuses were augmented at random with PAB (n=10) (control group); a mixture of PAB and beta-tricalcium phosphate (Β-TCP) (n=10) (experimental group); or a mixture of PAB, Β-TCP, and hydroxyapatite (HA) (n=10) (experimental group). A sample of each graft material was obtained at time of maxillary sinus augmentation, and microcomputed tomography (Μ-CT) analyses were performed. Five months later, samples of the augmented areas (n=23) were harvested by means of a trephine bur, and Μ-CT analyses of these samples were performed. Density values for the bone were compared to the data obtained 5 months before from the original material. RESULTS: All groups showed increasing density values after a healing time of 5 months. Because of a high dropout rate, the sample size was too small to compare the groups statistically. CONCLUSIONS: Bone density increased after maxillary sinus augmentation for both PAB alone or in combination with substitute materials based on HA and/or Β-TCP particles. A larger sample size and a split-mouth design would help to reliably reveal significant differences between the single materials.
Authors: Emanuele Clozza; Marcel Obrecht; Michel Dard; Paulo G Coelho; Christer Dahlin; Steven P Engebretson Journal: Clin Oral Investig Date: 2013-08-10 Impact factor: 3.573
Authors: Eliyahu Shavit; Ilana Shavit; Daniel Pinchasov; David Shavit; Ginnady Pinchasov; Gintaras Juodzbalys Journal: J Oral Maxillofac Res Date: 2019-06-30