Literature DB >> 23188053

A thermally-stable enzyme detection assay that amplifies signal autonomously in water without assistance from biological reagents.

Kimy Yeung1, Kyle M Schmid, Scott T Phillips.   

Abstract

This Communication describes a thermally-stable small molecule and a corresponding assay strategy that autonomously amplifies a colorimetric signal when a specific enzyme biomarker is detected.

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Year:  2012        PMID： 23188053     DOI： 10.1039/c2cc36861g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

Review 1.  Polymeric Nanostructures for Imaging and Therapy.

Authors:  Mahmoud Elsabahy; Gyu Seong Heo; Soon-Mi Lim; Guorong Sun; Karen L Wooley
Journal:  Chem Rev       Date:  2015-08-04       Impact factor: 60.622

2.  Alcohol, Aldehyde, and Ketone Liberation and Intracellular Cargo Release through Peroxide-Mediated α-Boryl Ether Fragmentation.

Authors:  Ramsey D Hanna; Yuta Naro; Alexander Deiters; Paul E Floreancig
Journal:  J Am Chem Soc       Date:  2016-09-30       Impact factor: 15.419

3.  Stimuli-Responsive Polymer Film that Autonomously Translates a Molecular Detection Event into a Macroscopic Change in Its Optical Properties via a Continuous, Thiol-Mediated Self-Propagating Reaction.

Authors:  Hemakesh Mohapatra; Hyungwoo Kim; Scott T Phillips
Journal:  J Am Chem Soc       Date:  2015-09-23       Impact factor: 15.419

4.  Quantitative Fluorescence Assays Using a Self-Powered Paper-Based Microfluidic Device and a Camera-Equipped Cellular Phone.

Authors:  Nicole K Thom; Gregory G Lewis; Kimy Yeung; Scott T Phillips
Journal:  RSC Adv       Date:  2014-01-01       Impact factor: 3.361

5.  A Strategy for Minimizing Background Signal in Autoinductive Signal Amplification Reactions for Point-of-Need Assays.

Authors:  Adam D Brooks; Kimy Yeung; Gregory G Lewis; Scott T Phillips
Journal:  Anal Methods       Date:  2015-03-06       Impact factor: 2.896

6.  Self-Propagating Amplification Reactions for Molecular Detection and Signal Amplification: Advantages, Pitfalls, and Challenges.

Authors:  Xiaolong Sun; Doron Shabat; Scott T Phillips; Eric V Anslyn
Journal:  J Phys Org Chem       Date:  2018-03-23       Impact factor: 2.391

7.  Signal transduction and amplification through enzyme-triggered ligand release and accelerated catalysis.

Authors:  Sean Goggins; Barrie J Marsh; Anneke T Lubben; Christopher G Frost
Journal:  Chem Sci       Date:  2015-06-15       Impact factor: 9.825

8.  Polymeric materials that convert local fleeting signals into global macroscopic responses.

Authors:  Hyungwoo Kim; Matthew S Baker; Scott T Phillips
Journal:  Chem Sci       Date:  2015-04-09       Impact factor: 9.825

9.  Exponential amplification by redox cross-catalysis and unmasking of doubly protected molecular probes.

Authors:  Justine Pallu; Charlie Rabin; Pan Hui; Thamires S Moreira; Geordie Creste; Corentin Calvet; Benoît Limoges; François Mavré; Mathieu Branca
Journal:  Chem Sci       Date:  2022-02-11       Impact factor: 9.825

10.  In Situ Generated Novel 1H MRI Reporter for β-Galactosidase Activity Detection and Visualization in Living Tumor Cells.

Authors:  Shuo Gao; Lei Zhao; Zhiqiang Fan; Vikram D Kodibagkar; Li Liu; Hanqin Wang; Hong Xu; Mingli Tu; Bifu Hu; Chuanbin Cao; Zhenjian Zhang; Jian-Xin Yu
Journal:  Front Chem       Date:  2021-07-15       Impact factor: 5.221
  10 in total

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