| Literature DB >> 23187132 |
Rosemary V Sampogna1, Qais Al-Awqati.
Abstract
In the kidney, the slit diaphragm joins adjacent podocytes, forming an epithelial barrier that filters plasma into the urinary space, yet retains blood cells and proteins within the circulation. In this issue of the JCI, Soda et al. have identified clathrin-mediated endocytosis as a central mechanism by which the function and structural integrity of the slit diaphragm are maintained.Mesh:
Substances:
Year: 2012 PMID: 23187132 PMCID: PMC3533562 DOI: 10.1172/JCI65785
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808