| Literature DB >> 23186727 |
Takaaki Kubota1, Yuichiro Ishiguro, Azusa Takahashi-Nakaguchi, Jane Fromont, Tohru Gonoi, Jun'ichi Kobayashi.
Abstract
Three new polyketides, manzamenones L-N (1-3), have been isolated from an Okinawan marine sponge of the genus Plakortis. The structures of 1-3 were elucidated on the basis of spectroscopic data. Manzamenones L-N (1-3) were new dimeric fatty-acid derivatives consisting of a tetrahydroindenone with three carboxy groups and two hexadecanyl chains. Manzamenones M (2) and N (3) showed antimicrobial activity against several bacteria and fungi.Entities:
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Year: 2012 PMID： 23186727 DOI： 10.1016/j.bmcl.2012.10.109
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823