Literature DB >> 23184722

Enhanced enzymatic thermal stability and activity in functionalized mesoporous silica monitored by (31) p NMR.

Kheireddine El-Boubbou1, David A Schofield, Christopher C Landry.   

Abstract

Organophosphorus hydrolase (OPH) is immobilized on ammonium-modified mesoporous silica particles. Thermal stability and activity are measured with a (31) P NMR assay of the conversion of paraoxon (toxic) to its non-toxic hydrolysis product. After immobilization, OPH is significantly more active at room temperature and retained activity even after being heated to 45 °C for 1 month.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID: 23184722     DOI: 10.1002/adhm.201100024

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN: 2192-2640            Impact factor:   9.933


  4 in total

1.  Fabrication of large-pore mesoporous Ca-Si-based bioceramics for bone regeneration.

Authors:  Deliang Zeng; Xingdi Zhang; Xiao Wang; Lingyan Cao; Ao Zheng; Jiahui Du; Yongsheng Li; Qingfeng Huang; Xinquan Jiang
Journal:  Int J Nanomedicine       Date:  2017-11-15

2.  Burkholderia cepacia lipase immobilized on heterofunctional magnetic nanoparticles and its application in biodiesel synthesis.

Authors:  Kai Li; Yanli Fan; Yaojia He; Leping Zeng; Xiaotao Han; Yunjun Yan
Journal:  Sci Rep       Date:  2017-11-28       Impact factor: 4.379

3.  Preparation of iron oxide mesoporous magnetic microparticles as novel multidrug carriers for synergistic anticancer therapy and deep tumor penetration.

Authors:  Kheireddine El-Boubbou; Rizwan Ali; Hajar Al-Zahrani; Thadeo Trivilegio; Abdullah H Alanazi; Abdul Latif Khan; Mohamed Boudjelal; Abdulmohsen AlKushi
Journal:  Sci Rep       Date:  2019-07-01       Impact factor: 4.379

4.  Iron Oxide Mesoporous Magnetic Nanostructures with High Surface Area for Enhanced and Selective Drug Delivery to Metastatic Cancer Cells.

Authors:  Kheireddine El-Boubbou; Rizwan Ali; Sulaiman Al-Humaid; Alshaimaa Alhallaj; O M Lemine; Mohamed Boudjelal; Abdulmohsen AlKushi
Journal:  Pharmaceutics       Date:  2021-04-14       Impact factor: 6.321

  4 in total

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