Literature DB >> 23182806

Generic antiepileptic drug prescribing: a cross-sectional study.

Jennifer Meyer1, David Fardo, Steven T Fleming, Claudia Hopenhayn, Yevgeniya Gokun, Melody Ryan.   

Abstract

The use of generic antiepileptic drugs (AEDs) in patients with epilepsy is controversial. The purpose of this study is to identify patient characteristics associated with increased odds of receiving a generic AED product. A large commercial database was used to identify patients with a primary diagnosis of epilepsy who were prescribed an AED during a three-month window. Data analysis found that those ≥65 years old had 15.7% greater odds of receiving a generic AED (OR = 1.157; 95% CI = 1.056-1.268). Patients with Medicaid were found to have 2.44 times the odds of having had a generic AED prescription (OR = 2.44; CI = 2.168-2.754). Patients residing in the Northeast had 12.6% decreased odds of receiving a generic AED (OR = 0.874; C I= 0.821-0.931). These patient characteristics could signify certain health care disparities and may represent potential confounders to future observational studies. Published by Elsevier Inc.

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Year:  2012        PMID: 23182806      PMCID: PMC4278569          DOI: 10.1016/j.yebeh.2012.10.010

Source DB:  PubMed          Journal:  Epilepsy Behav        ISSN: 1525-5050            Impact factor:   3.337


  17 in total

1.  Position statement on the coverage of anticonvulsant drugs for the treatment of epilepsy.

Authors:  K Liow; G L Barkley; J R Pollard; C L Harden; C W Bazil
Journal:  Neurology       Date:  2007-04-17       Impact factor: 9.910

2.  Generic substitution of antiepileptics: need for a balanced view.

Authors:  Gregory M Peterson
Journal:  CNS Spectr       Date:  2011-08       Impact factor: 3.790

3.  Generic antiepileptic drugs and associated medical resource utilization in the United States.

Authors:  D M Labiner; P E Paradis; R Manjunath; M S Duh; M-H Lafeuille; D Latrémouille-Viau; P Lefebvre; S L Helmers
Journal:  Neurology       Date:  2010-04-14       Impact factor: 9.910

4.  Generic-only drug coverage in the Medicare Part D gap and effect on medication cost-cutting behaviors for patients with diabetes mellitus: the translating research into action for diabetes study.

Authors:  O Kenrik Duru; Carol M Mangione; John Hsu; W Neil Steers; Elaine Quiter; Norman Turk; Susan L Ettner; Julie A Schmittdiel; Chien-Wen Tseng
Journal:  J Am Geriatr Soc       Date:  2010-04-06       Impact factor: 5.562

5.  Acute epilepsy exacerbations in patients switched between A-rated anti-epileptic drugs.

Authors:  Scott T Devine; Edmond Weisbart; John Barron; Andrew Behm
Journal:  Curr Med Res Opin       Date:  2010-02       Impact factor: 2.580

6.  Association between antiepileptic drug switching and epilepsy-related events.

Authors:  Ryan N Hansen; Jonathan D Campbell; Sean D Sullivan
Journal:  Epilepsy Behav       Date:  2009-07-16       Impact factor: 2.937

7.  Chronic disease medication use in managed care and indemnity insurance plans.

Authors:  Randall S Stafford; Stephen M Davidson; Harriet Davidson; Heidi Miracle-McMahill; Sybil L Crawford; David Blumenthal
Journal:  Health Serv Res       Date:  2003-04       Impact factor: 3.402

8.  Patient perception of generic antiepileptic drugs in the Midwestern United States.

Authors:  Tania Beltran Papsdorf; Elizabeth Ablah; Surya Ram; Toni Sadler; Kore Liow
Journal:  Epilepsy Behav       Date:  2008-10-30       Impact factor: 2.937

9.  Sociodemographic differences in antiepileptic drug prescriptions to adult epilepsy patients.

Authors:  P Mattsson; T Tomson; O Eriksson; L Brännström; G Ringbäck Weitoft
Journal:  Neurology       Date:  2010-01-26       Impact factor: 9.910

10.  Determinants of generic drug substitution in Switzerland.

Authors:  Anne Decollogny; Yves Eggli; Patricia Halfon; Thomas M Lufkin
Journal:  BMC Health Serv Res       Date:  2011-01-26       Impact factor: 2.655

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  2 in total

1.  Comparison of brand versus generic antiepileptic drug adverse event reporting rates in the U.S. Food and Drug Administration Adverse Event Reporting System (FAERS).

Authors:  Md Motiur Rahman; Yasser Alatawi; Ning Cheng; Jingjing Qian; Annya V Plotkina; Peggy L Peissig; Richard L Berg; David Page; Richard A Hansen
Journal:  Epilepsy Res       Date:  2017-06-13       Impact factor: 3.045

2.  Estimating Generic Drug Use with Electronic Health Records Data from a Health Care Delivery System: Implications for Quality Improvement and Research.

Authors:  Vani Nimbal; Jodi B Segal; Robert J Romanelli
Journal:  J Manag Care Spec Pharm       Date:  2016-10
  2 in total

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