Literature DB >> 23178627

Association of socio-economic status and stage of pancreatic cancer at time of surgery in a German setting.

Jens Standop1, Yvonne Kuhn, Tim R Glowka, Nico Schaefer, Marcus Overhaus, Volker Schmitz, Andreas Hirner, Jorg C Kalff.   

Abstract

BACKGROUND/AIMS: Curative resection has been proven to be one of the most important factors determining outcome in pancreatic cancer patients. Advanced stage of pancreatic cancer at diagnosis is strongly associated with a low socioeconomic status (SES), and patients from affluent areas have better cancer survival than patients from deprived areas. We tested, in our population of pancreatic cancer patients, the hypothesis that surrogates representing a lower SES or demographic factors (DGF) linked to rural areas are associated with a more advanced disease stage at presentation.
METHODOLOGY: Between 1989 and 2008, patients with pancreatic adenocarcinoma and pancreaticoduodenectomy were identified from our pancreatic resection database. DGF, SES surrogates and tumor stage were obtained from patients' files together with pathology reports, a residents' registration office questionnaire and telephone interviews with patients and family members.
RESULTS: Follow-up was completed in 117 patients. There were no significant differences regarding tumor stage (local size and lymph node metastases), or the likelihood of negative resection margins in relation to the patients' DGF or any surrogate parameters for SES. Furthermore, comparison of two different treatment periods showed no significant advances regarding secondary cancer prevention within 20 years.
CONCLUSIONS: Longer waiting times for appointments combined with less sensitive imaging techniques and consecutive later referral to a cancer specialist are likely to be associated with inferior quality of medical results. Therefore, a lively debate is currently underway in Germany concerning the harmonization of reimbursement modes for statutory and private health insurance. Our data with no negative correlation of low SES or unfavorable DGF and disease stage at time of presentation or the likelihood for a curative resection, do not promote the universal accusation of health care disparities solely based on economic issues in Germany.

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Year:  2012        PMID: 23178627     DOI: 10.5754/hge10334

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  5 in total

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Authors:  Margaret Wahutu; Sara K Vesely; Janis Campbell; Anne Pate; Alicia L Salvatore; Amanda E Janitz
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2.  Standardized cancer incidence disparities in Upper Manhattan New York City neighborhoods: the role of race/ethnicity, socioeconomic status, and known risk factors.

Authors:  Dana Hashim; Zeinab Farhat; Sylvan Wallenstein; Marta Manczuk; Randall F Holcombe; Lorna Thorpe; Maria J Schymura; Roberto G Lucchini; Paolo Boffetta
Journal:  Eur J Cancer Prev       Date:  2016-07       Impact factor: 2.497

3.  Variation in insurance status by patient demographics and tumor site among nonelderly adult patients with cancer.

Authors:  Stephen R Grant; Gary V Walker; B Ashleigh Guadagnolo; Matthew Koshy; Pamela K Allen; Usama Mahmood
Journal:  Cancer       Date:  2015-04-27       Impact factor: 6.860

4.  Population-based study of the impact of surgical and adjuvant therapy at the same or a different institution on survival of patients with pancreatic adenocarcinoma.

Authors:  N Latchana; L Davis; N G Coburn; A Mahar; Y Liu; A Hammad; D Kagedan; M Elmi; M Siddiqui; C C Earle; J Hallet
Journal:  BJS Open       Date:  2018-12-05

5.  Pathologic Diagnosis of Pancreatic Adenocarcinoma in the United States: Its Status and Prognostic Value.

Authors:  Miaozhen Qiu; Huijuan Qiu; Ying Jin; Xiaoli Wei; Yixin Zhou; Zixian Wang; Deshen Wang; Chao Ren; Huiyan Luo; Feng Wang; Dongsheng Zhang; Fenghua Wang; Yuhong Li; Dajun Yang; Ruihua Xu
Journal:  J Cancer       Date:  2016-03-26       Impact factor: 4.207

  5 in total

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