Literature DB >> 23178464

Functional and molecular insights into KSRP function in mRNA decay.

Paola Briata1, Ching-Yi Chen, Andres Ramos, Roberto Gherzi.   

Abstract

KSRP is a single strand nucleic acid binding protein that controls gene expression at multiple levels. In this review we focus on the recent molecular, cellular, and structural insights into the mRNA decay promoting function of KSRP. We discuss also some aspects of KSRP-dependent microRNA maturation from precursors that are related to its mRNA destabilizing function. This article is part of a Special Issue entitled: RNA Decay mechanisms.
Copyright © 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID: 23178464     DOI: 10.1016/j.bbagrm.2012.11.003

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  30 in total

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Journal:  Mol Cell Biol       Date:  2014-08-25       Impact factor: 4.272

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Authors:  Pedro Miura; Piero Sanfilippo; Sol Shenker; Eric C Lai
Journal:  Bioessays       Date:  2014-06-05       Impact factor: 4.345

3.  Hsp70's RNA-binding and mRNA-stabilizing activities are independent of its protein chaperone functions.

Authors:  Aparna Kishor; Elizabeth J F White; Aerielle E Matsangos; Zisui Yan; Bishal Tandukar; Gerald M Wilson
Journal:  J Biol Chem       Date:  2017-07-05       Impact factor: 5.157

4.  HnRNP A1 tethers KSRP to an exon splicing silencer that inhibits an erythroid-specific splicing event in PU.1-induced erythroleukemia.

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5.  KH-Type Splicing Regulatory Protein Controls Colorectal Cancer Cell Growth and Modulates the Tumor Microenvironment.

Authors:  Francesco Caiazza; Katarzyna Oficjalska; Miriam Tosetto; James J Phelan; Sinéad Noonan; Petra Martin; Kate Killick; Laura Breen; Fiona O'Neill; Blathnaid Nolan; Simon Furney; Robert Power; David Fennelly; Charles S Craik; Jacintha O'Sullivan; Kieran Sheahan; Glen A Doherty; Elizabeth J Ryan
Journal:  Am J Pathol       Date:  2019-08-09       Impact factor: 4.307

6.  SRI-42127, a novel small molecule inhibitor of the RNA regulator HuR, potently attenuates glial activation in a model of lipopolysaccharide-induced neuroinflammation.

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Journal:  Glia       Date:  2021-09-17       Impact factor: 7.452

Review 7.  Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease.

Authors:  Paola Briata; Domenico Bordo; Margherita Puppo; Franco Gorlero; Martina Rossi; Nora Perrone-Bizzozero; Roberto Gherzi
Journal:  Wiley Interdiscip Rev RNA       Date:  2015-12-27       Impact factor: 9.957

8.  Transgenic expression of HuR increases vasogenic edema and impedes functional recovery in rodent ischemic stroke.

Authors:  Agnieszka A Ardelt; Randall S Carpenter; Ifeanyi Iwuchukwu; An Zhang; William Lin; Ewa Kosciuczuk; Cyrus Hinkson; Tania Rebeiz; Sydney Reitz; Peter H King
Journal:  Neurosci Lett       Date:  2017-10-02       Impact factor: 3.046

Review 9.  Post-translational Control of RNA-Binding Proteins and Disease-Related Dysregulation.

Authors:  Alejandro Velázquez-Cruz; Blanca Baños-Jaime; Antonio Díaz-Quintana; Miguel A De la Rosa; Irene Díaz-Moreno
Journal:  Front Mol Biosci       Date:  2021-04-27

10.  A new KSRP-binding compound suppresses distant metastasis of colorectal cancer by targeting the oncogenic KITENIN complex.

Authors:  Jeong A Bae; Woo Kyun Bae; Sung Jin Kim; Yoo-Seung Ko; Keon Young Kim; So-Yeon Park; Young Hyun Yu; Eun Ae Kim; Ik Joo Chung; Hangun Kim; Hyung-Ho Ha; Kyung Keun Kim
Journal:  Mol Cancer       Date:  2021-05-26       Impact factor: 27.401

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