Literature DB >> 2317773

Monosomy 3 and isochromosome 8q in a uveal melanoma.

D E Horsman1, H Sroka, J Rootman, V A White.   

Abstract

Chromosome analysis of a locally invasive uveal melanoma revealed monosomy 3 and i(8q). Sublines with multiple copies of the i(8q) were also present. Loss of heterozygosity for genes on chromosome 3 and duplication of genes on 8q may play an important role in progression of uveal melanoma.

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Year:  1990        PMID: 2317773     DOI: 10.1016/0165-4608(90)90090-w

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  33 in total

1.  The molecular classification of uveal melanocytic lesions: an important discovery in context.

Authors:  Robert Folberg
Journal:  J Mol Diagn       Date:  2010-06-03       Impact factor: 5.568

2.  Integrative Copy Number Analysis of Uveal Melanoma Reveals Novel Candidate Genes Involved in Tumorigenesis Including a Tumor Suppressor Role for PHF10/BAF45a.

Authors:  Hima Anbunathan; Ruth Verstraten; Arun D Singh; J William Harbour; Anne M Bowcock
Journal:  Clin Cancer Res       Date:  2019-06-21       Impact factor: 12.531

Review 3.  The genetics of uveal melanoma: an emerging framework for targeted therapy.

Authors:  J William Harbour
Journal:  Pigment Cell Melanoma Res       Date:  2012-02-13       Impact factor: 4.693

4.  Symptomatic Liver Metastasis Prompting Diagnosis of Uveal Melanoma.

Authors:  Caroline C Awh; Matthew W Wilson
Journal:  Ocul Oncol Pathol       Date:  2019-10-21

5.  Prediction of prognosis in patients with uveal melanoma using fluorescence in situ hybridisation.

Authors:  K A Patel; N D Edmondson; F Talbot; M A Parsons; I G Rennie; K Sisley
Journal:  Br J Ophthalmol       Date:  2001-12       Impact factor: 4.638

Review 6.  Recent developments in prognostic and predictive testing in uveal melanoma.

Authors:  Matthew G Field; J William Harbour
Journal:  Curr Opin Ophthalmol       Date:  2014-05       Impact factor: 3.761

Review 7.  Molecular pathology of uveal melanoma.

Authors:  S E Coupland; S L Lake; M Zeschnigk; B E Damato
Journal:  Eye (Lond)       Date:  2012-12-07       Impact factor: 3.775

8.  Expression patterns of cyclin D1 and related proteins regulating G1-S phase transition in uveal melanoma and retinoblastoma.

Authors:  S E Coupland; N Bechrakis; A Schüler; I Anagnostopoulos; M Hummel; N Bornfeld; H Stein
Journal:  Br J Ophthalmol       Date:  1998-08       Impact factor: 4.638

9.  Genetics of uveal melanoma and cutaneous melanoma: two of a kind?

Authors:  Thomas van den Bosch; Emine Kilic; Dion Paridaens; Annelies de Klein
Journal:  Dermatol Res Pract       Date:  2010-06-06

Review 10.  Emerging insights into the molecular pathogenesis of uveal melanoma.

Authors:  Solange Landreville; Olga A Agapova; J William Harbour
Journal:  Future Oncol       Date:  2008-10       Impact factor: 3.404

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