Literature DB >> 23176375

Acupuncture for cerebral vasospasm after subarachnoid hemorrhage: a retrospective case-control study.

Chang-Nam Ko1, In-Whan Lee, Seung-Yeon Cho, Seung Hwan Lee, Seong-Uk Park, Jun Seok Koh, Jung-Mi Park, Gook Ki Kim, Hyung-Sup Bae.   

Abstract

OBJECTIVES: To examine the possibility of acupuncture as a new promising treatment to prevent delayed cerebral vasospasm, retrospective comparison was done of patient outcomes in patients with subarachnoid hemorrhage (SAH) treated with and without acupuncture.
MATERIALS AND METHODS: Twenty (20) patients with SAH were treated after their ruptured aneurysms had been secured. Acupuncture treatments were applied to the bilateral Zusanli (ST36) and Neiguan (PC6) once a day for 2 weeks, starting within 3 days of the aneurysm rupture. The incidence of angiographic vasospasm and delayed ischemic neurological deficit (DIND), the patient's functional status at discharge, and mortality rate were analyzed. Patient outcomes were compared with those of an age- and severity-matched comparison group composed of patients treated in the hospital without acupuncture.
RESULTS: None of the patients who received acupuncture died. Angiographic vasospasms occurred in 5 patients (25.0%) and DIND in 2 (10%). In terms of functional impairment, the modified Rankin score at discharge was ≤2 in 7 patients (35%). In the control group, angiographic vasospasms occurred in 10 patients (55.6%) and DIND in 7 (38.9%), similar to the reported incidence in conventionally treated patients.
CONCLUSIONS: Patients with SAH who received acupuncture had a significantly lower incidence of DIND and significantly improved function at discharge, suggesting that acupuncture is effective in preventing cerebral vasospasm. In light of these promising results, a randomized controlled trial is warranted to determine the efficacy of acupuncture in a clinical setting.

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Year:  2012        PMID: 23176375     DOI: 10.1089/acm.2012.0076

Source DB:  PubMed          Journal:  J Altern Complement Med        ISSN: 1075-5535            Impact factor:   2.579


  5 in total

1.  The efficacy and safety of acupuncture for cerebral vasospasm after subarachnoid hemorrhage: study protocol for a randomized controlled trial.

Authors:  Seung-Yeon Cho; Dong-Hyuk Lee; Hee Sup Shin; Seung Hwan Lee; Jun Seok Koh; Woo-Sang Jung; Sang-Kwan Moon; Jung-Mi Park; Chang-Nam Ko; Ho Kim; Seong-Uk Park
Journal:  Trials       Date:  2015-02-28       Impact factor: 2.279

2.  Electroacupuncture at GV20 and ST36 Exerts Neuroprotective Effects via the EPO-Mediated JAK2/STAT3 Pathway in Cerebral Ischemic Rats.

Authors:  Hong Xu; Ya-Min Zhang; Hua Sun; Su-Hui Chen; Ying-Kui Si
Journal:  Evid Based Complement Alternat Med       Date:  2017-08-07       Impact factor: 2.629

3.  Acupuncture promotes functional recovery after cerebral hemorrhage by upregulating neurotrophic factor expression.

Authors:  Dan Li; Qiu-Xin Chen; Wei Zou; Xiao-Wei Sun; Xue-Ping Yu; Xiao-Hong Dai; Wei Teng
Journal:  Neural Regen Res       Date:  2020-08       Impact factor: 5.135

4.  Electroacupuncture improves recovery after hemorrhagic brain injury by inducing the expression of angiopoietin-1 and -2 in rats.

Authors:  Hua-Jun Zhou; Tao Tang; Jian-Hua Zhong; Jie-Kun Luo; Han-Jin Cui; Qi-Mei Zhang; Jing-Hua Zhou; Qiang Zhang
Journal:  BMC Complement Altern Med       Date:  2014-04-05       Impact factor: 3.659

5.  Regulatory T Cells Contribute to the Inhibition of Radiation-Induced Acute Lung Inflammation via Bee Venom Phospholipase A₂ in Mice.

Authors:  Dasom Shin; Gihyun Lee; Sung-Hwa Sohn; Soojin Park; Kyung-Hwa Jung; Ji Min Lee; Jieun Yang; Jaeho Cho; Hyunsu Bae
Journal:  Toxins (Basel)       Date:  2016-04-30       Impact factor: 4.546

  5 in total

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