Literature DB >> 23176156

The value of screening signal-to-cutoff ratios for hepatitis C virus antibody confirmation.

Susan L Stramer1, Roger Y Dodd, Jaye P Brodsky.   

Abstract

A licensed recombinant immunoblot assay (RIBA) has been an integral component of the algorithm for confirmation of reactivity for antibody to hepatitis C virus in screening assays. This test may become unavailable in the future, so we have investigated the potential value of screening test signal values to support confirmation. Depending on the screening test used (Ortho enzyme-linked immunosorbent assay or Abbott PRISM chemiluminescent assay), signal-to-cutoff ratios of 5.00 and 3.20, respectively, were shown to have positive predictive values of 89.1 and 95%, with sensitivities of 93.1 and 88.7% relative to RIBA. However, additional steps will have to be added to assure equivalent performance to RIBA.
© 2012 American Association of Blood Banks.

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Year:  2012        PMID： 23176156     DOI： 10.1111/j.1537-2995.2012.03955.x

Source DB:  PubMed          Journal:  Transfusion        ISSN： 0041-1132            Impact factor:   3.157


  7 in total

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2.  Diagnostic challenges of hepatitis C.

Authors:  Monica A Konerman; Anna S Lok
Journal:  JAMA       Date:  2014-06-25       Impact factor: 56.272

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4.  Vital signs: evaluation of hepatitis C virus infection testing and reporting - eight U.S. sites, 2005-2011.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2013-05-10       Impact factor: 17.586

5.  Role of signal-to-cut-off ratios of anti-hepatitis C virus antibody by enzyme immunoassays along with ID-NAT for screening of whole blood donors in India.

Authors:  Satyam Arora; Veena Doda
Journal:  Asian J Transfus Sci       Date:  2016 Jan-Jun

6.  The Role of the Signal-to-Cutoff Ratio in Automated Anti-HCV Chemiluminescent Immunoassays by Referring to the Nucleic Acid Amplification Test and the Recombinant Immunoblot Assay.

Authors:  Moon Suk Choi; Kyunghoon Lee; Yun Ji Hong; Eun Young Song; Dal Sik Kim; Junghan Song
Journal:  Ann Lab Med       Date:  2018-09       Impact factor: 3.464

Review 7.  Residual risk of HIV, HCV, and HBV transmission by blood transfusion between 2015 and 2017 at the Regional Blood Transfusion Center of Ouagadougou, Burkina Faso.

Authors:  Arzouma Paul Yooda; Salam Sawadogo; Serge Théophile Soubeiga; Dorcas Obiri-Yeboah; Koumpingnin Nebie; Abdoul Karim Ouattara; Birama Diarra; Abibou Simpore; Yetema Dieudonné Yonli; Abdoul-Guaniyi Sawadogo; Bia Emile Drabo; Seimbou Zalla; Anita Pierrette Siritié; Rodrigue Sosthène Nana; Honorine Dahourou; Jacques Simpore
Journal:  J Blood Med       Date:  2019-02-01
  7 in total

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