Literature DB >> 23175122

Human tumour viruses and the deregulation of cell polarity in cancer.

Lawrence Banks1, David Pim, Miranda Thomas.   

Abstract

The role of cell polarity regulators in the development of cancer has long been an enigma. Despite displaying characteristics of tumour suppressors, the core regulators of polarity are rarely mutated in tumours and there are few data from animal models to suggest that they directly contribute to cancer susceptibility, thus questioning their relevance to human carcinogenesis. However, a body of data from human tumour viruses is now providing compelling evidence of a central role for the perturbation of cell polarity in the development of cancer.

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Year:  2012        PMID： 23175122     DOI： 10.1038/nrc3400

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  123 in total

1.  Identification of Vangl2 and Scrb1 as planar polarity genes in mammals.

Authors:  Mireille Montcouquiol; Rivka A Rachel; Pamela J Lanford; Neal G Copeland; Nancy A Jenkins; Matthew W Kelley
Journal:  Nature       Date:  2003-04-30       Impact factor: 49.962

Review 2.  HIV-1 pathogenesis.

Authors:  Mario Stevenson
Journal:  Nat Med       Date:  2003-07       Impact factor: 53.440

3.  Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene.

Authors:  G Caruana; A Bernstein
Journal:  Mol Cell Biol       Date:  2001-03       Impact factor: 4.272

4.  SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.

Authors:  Helen B Pearson; Pedro A Perez-Mancera; Lukas E Dow; Andrew Ryan; Pierre Tennstedt; Debora Bogani; Imogen Elsum; Andy Greenfield; David A Tuveson; Ronald Simon; Patrick O Humbert
Journal:  J Clin Invest       Date:  2011-10-03       Impact factor: 14.808

5.  PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6.

Authors:  Carina H Storrs; Saul J Silverstein
Journal:  J Virol       Date:  2007-02-07       Impact factor: 5.103

6.  Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells.

Authors:  Christopher A Johnston; Keiko Hirono; Kenneth E Prehoda; Chris Q Doe
Journal:  Cell       Date:  2009-09-18       Impact factor: 41.582

7.  Cdc42, Par6, and aPKC regulate Arp2/3-mediated endocytosis to control local adherens junction stability.

Authors:  Marios Georgiou; Eliana Marinari; Jemima Burden; Buzz Baum
Journal:  Curr Biol       Date:  2008-10-30       Impact factor: 10.834

8.  siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells.

Authors:  Karin Butz; Tutik Ristriani; Arnd Hengstermann; Claudia Denk; Martin Scheffner; Felix Hoppe-Seyler
Journal:  Oncogene       Date:  2003-09-04       Impact factor: 9.867

9.  Epigenetic repression of E-cadherin expression by hepatitis B virus x antigen in liver cancer.

Authors:  A Arzumanyan; T Friedman; E Kotei; I O L Ng; Z Lian; M A Feitelson
Journal:  Oncogene       Date:  2011-06-27       Impact factor: 9.867

10.  Depletion of Langerhans cells in human papillomavirus type 16-infected skin is associated with E6-mediated down regulation of E-cadherin.

Authors:  Kate Matthews; Cheng Mee Leong; Lindsay Baxter; Emma Inglis; Kankatsu Yun; B Thomas Bäckström; John Doorbar; Merilyn Hibma
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103
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  27 in total

1.  The Human Papillomavirus E6 PDZ Binding Motif Links DNA Damage Response Signaling to E6 Inhibition of p53 Transcriptional Activity.

Authors:  Jayashree Thatte; Paola Massimi; Miranda Thomas; Siaw Shi Boon; Lawrence Banks
Journal:  J Virol       Date:  2018-07-31       Impact factor: 5.103

2.  Human Papillomavirus 16 (HPV-16), HPV-18, and HPV-31 E6 Override the Normal Phosphoregulation of E6AP Enzymatic Activity.

Authors:  Jayashree Thatte; Lawrence Banks
Journal:  J Virol       Date:  2017-10-27       Impact factor: 5.103

3.  Cancer-causing human papillomavirus E6 proteins display major differences in the phospho-regulation of their PDZ interactions.

Authors:  Siaw Shi Boon; Vjekoslav Tomaić; Miranda Thomas; Sally Roberts; Lawrence Banks
Journal:  J Virol       Date:  2014-11-19       Impact factor: 5.103

Review 4.  Molecular Mechanisms of HIV Protease Inhibitors Against HPV-Associated Cervical Cancer: Restoration of TP53 Tumour Suppressor Activities.

Authors:  Lilian Makgoo; Salerwe Mosebi; Zukile Mbita
Journal:  Front Mol Biosci       Date:  2022-05-10

5.  Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse.

Authors:  Idella F Yamben; Rivka A Rachel; Shalini Shatadal; Neal G Copeland; Nancy A Jenkins; Soren Warming; Anne E Griep
Journal:  Dev Biol       Date:  2013-10-01       Impact factor: 3.582

6.  Human papillomavirus (HPV)-18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein.

Authors:  Florencia Facciuto; Marina Bugnon Valdano; Federico Marziali; Paola Massimi; Lawrence Banks; Ana Laura Cavatorta; Daniela Gardiol
Journal:  Mol Oncol       Date:  2014-01-14       Impact factor: 6.603

Review 7.  Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4.

Authors:  Johanna I Partanen; Topi A Tervonen; Juha Klefström
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2013-09-23       Impact factor: 6.237

Review 8.  The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation.

Authors:  James A Scarth; Molly R Patterson; Ethan L Morgan; Andrew Macdonald
Journal:  J Gen Virol       Date:  2021-01-11       Impact factor: 3.891

9.  Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer.

Authors:  Aubhishek Zaman; Xiaofeng Wu; Andrew Lemoff; Sivaramakrishna Yadavalli; Jeon Lee; Chensu Wang; Jonathan Cooper; Elizabeth A McMillan; Charles Yeaman; Hamid Mirzaei; Michael A White; Trever G Bivona
Journal:  Cell Rep       Date:  2021-08-03       Impact factor: 9.423

10.  PDZ domains and viral infection: versatile potentials of HPV-PDZ interactions in relation to malignancy.

Authors:  Kazunori Nagasaka; Kei Kawana; Yutaka Osuga; Tomoyuki Fujii
Journal:  Biomed Res Int       Date:  2013-09-04       Impact factor: 3.411
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