Literature DB >> 23174531

NIH TRND program: successes in preclinical therapeutic development.

John C McKew1, Andre M Pilon.   

Abstract

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Year:  2012        PMID： 23174531      PMCID： PMC3814034          DOI： 10.1016/j.tips.2012.10.001

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


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  7 in total

Review 1.  How to improve R&D productivity: the pharmaceutical industry's grand challenge.

Authors:  Steven M Paul; Daniel S Mytelka; Christopher T Dunwiddie; Charles C Persinger; Bernard H Munos; Stacy R Lindborg; Aaron L Schacht
Journal:  Nat Rev Drug Discov       Date:  2010-02-19       Impact factor: 84.694

2.  Sickle cell anemia, a molecular disease.

Authors:  L PAULING; H A ITANO
Journal:  Science       Date:  1949-04-29       Impact factor: 47.728

Review 3.  Lessons from 60 years of pharmaceutical innovation.

Authors:  Bernard Munos
Journal:  Nat Rev Drug Discov       Date:  2009-12       Impact factor: 84.694

4.  Reengineering translational science: the time is right.

Authors:  Francis S Collins
Journal:  Sci Transl Med       Date:  2011-07-06       Impact factor: 17.956

5.  Repurposing approved and abandoned drugs for the treatment and prevention of cancer through public-private partnership.

Authors:  Scott J Weir; Louis J DeGennaro; Christopher P Austin
Journal:  Cancer Res       Date:  2012-01-13       Impact factor: 12.701

Review 6.  The Valley of Death in anticancer drug development: a reassessment.

Authors:  David J Adams
Journal:  Trends Pharmacol Sci       Date:  2012-03-10       Impact factor: 14.819

Review 7.  Future directions of sickle cell disease research: the NIH perspective.

Authors:  W Keith Hoots; Susan B Shurin
Journal:  Pediatr Blood Cancer       Date:  2012-04-19       Impact factor: 3.167
  7 in total
  2 in total

1.  New Financial and Research Models for Pediatric Orphan Drug Development - Focus on the NCATS TRND Program.

Authors:  John Shen; Gurmit Grewal; Andre M Pilon; John C McKew
Journal:  Pharmaceut Med       Date:  2014-02-01

2.  Rare diseases research: expanding collaborative translational research opportunities.

Authors:  Stephen C Groft
Journal:  Chest       Date:  2013-07       Impact factor: 9.410
  2 in total

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