BACKGROUND: Physical activity is a critical component in the care of diabetes. Although it offers health benefits it presents challenges. OBJECTIVE: To investigate differences between adolescent boys and girls with type 1 diabetes and healthy controls in terms of maximal work capacity (VO(2) max) and hormonal response to physical exercise of different intensities. SUBJECTS: Twelve individuals (six boys and six girls; age 14-19 yr, pubertal stage 4-5) with type 1 diabetes (duration, 6.3 ± 4.4 yr; hemoglobin A1c, 63 ± 10 mmol/mol) were compared with 12 healthy controls matched for age, sex, pubertal stage, body mass index standard deviation score, and amount of regular physical activity. METHODS: During consecutive days, three different workloads; maximal, endurance, and interval, were performed on an Ergometer cycle. During the tests, levels of lactate, glucose, insulin, and regulatory hormones [glucagon, cortisol, growth hormone (GH), adrenaline, and noradrenaline] were measured in blood. Subcutaneous glucose was measured continuously. RESULTS: VO(2) max did not differ between the groups, diabetes 49.8 ± 9.9 vs. control 50.7 ± 12.0 mL/min/kg. Hormonal responses did not differ between the groups except for mean peak GH level during the interval test, diabetes 63.2 ± 27.0 vs. control 33.8 ± 20.9 mU/L, p < 0.05. CONCLUSIONS: Physical capacity and hormonal regulation of blood glucose in connection with physical exercise of different intensities did not differ between adolescents with diabetes and healthy controls. Thus, adolescents with type 1 diabetes can participate in physical activity on the same terms as healthy peers.
BACKGROUND: Physical activity is a critical component in the care of diabetes. Although it offers health benefits it presents challenges. OBJECTIVE: To investigate differences between adolescent boys and girls with type 1 diabetes and healthy controls in terms of maximal work capacity (VO(2) max) and hormonal response to physical exercise of different intensities. SUBJECTS: Twelve individuals (six boys and six girls; age 14-19 yr, pubertal stage 4-5) with type 1 diabetes (duration, 6.3 ± 4.4 yr; hemoglobin A1c, 63 ± 10 mmol/mol) were compared with 12 healthy controls matched for age, sex, pubertal stage, body mass index standard deviation score, and amount of regular physical activity. METHODS: During consecutive days, three different workloads; maximal, endurance, and interval, were performed on an Ergometer cycle. During the tests, levels of lactate, glucose, insulin, and regulatory hormones [glucagon, cortisol, growth hormone (GH), adrenaline, and noradrenaline] were measured in blood. Subcutaneous glucose was measured continuously. RESULTS: VO(2) max did not differ between the groups, diabetes 49.8 ± 9.9 vs. control 50.7 ± 12.0 mL/min/kg. Hormonal responses did not differ between the groups except for mean peak GH level during the interval test, diabetes 63.2 ± 27.0 vs. control 33.8 ± 20.9 mU/L, p < 0.05. CONCLUSIONS: Physical capacity and hormonal regulation of blood glucose in connection with physical exercise of different intensities did not differ between adolescents with diabetes and healthy controls. Thus, adolescents with type 1 diabetes can participate in physical activity on the same terms as healthy peers.
Authors: Karen M Rothacker; Sam Armstrong; Grant J Smith; Nat Benjanuvatra; Brendan Lay; Peter Adolfsson; Timothy W Jones; Paul A Fournier; Elizabeth A Davis Journal: Diabetologia Date: 2021-05-04 Impact factor: 10.122
Authors: Artur Myśliwiec; Maria Skalska; Arkadiusz Michalak; Jędrzej Chrzanowski; Małgorzata Szmigiero-Kawko; Agnieszka Lejk; Joanna Jastrzębska; Łukasz Radzimiński; Guillermo F López-Sánchez; Andrzej Gawrecki; Zbigniew Jastrzębski Journal: Int J Environ Res Public Health Date: 2021-01-15 Impact factor: 3.390
Authors: Isaac A Chávez-Guevara; Rosa P Hernández-Torres; Marina Trejo-Trejo; Everardo González-Rodríguez; Verónica Moreno-Brito; Abraham Wall-Medrano; Jorge A Pérez-León; Arnulfo Ramos-Jiménez Journal: Int J Environ Res Public Health Date: 2021-06-29 Impact factor: 3.390