Literature DB >> 2317114

Partial purification and characterisation of a synovial fluid inhibitor of osteoblasts.

R A Hazelton1, R Vedam, P P Masci, A N Whitaker.   

Abstract

A polypeptide inhibitor of osteoblast proliferation is described which occurs in synovial effusions of patients with rheumatoid arthritis. Partial purification of the inhibitor showed a molecular weight of approximately 81,000 by gel electrophoresis. This polypeptide seems to be unique as no inhibitor of osteoblasts of similar molecular weight has been previously described in rheumatoid synovial effusions.

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Year:  1990        PMID： 2317114      PMCID： PMC1003992          DOI： 10.1136/ard.49.2.121

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  15 in total

1.  DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.

Authors:  B J DAVIS
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

2.  The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors:  K Weber; M Osborn
Journal:  J Biol Chem       Date:  1969-08-25       Impact factor: 5.157

3.  Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors.

Authors:  D R Bertolini; G E Nedwin; T S Bringman; D D Smith; G R Mundy
Journal:  Nature       Date:  1986 Feb 6-12       Impact factor: 49.962

4.  Ultrasensitive stain for proteins in polyacrylamide gels shows regional variation in cerebrospinal fluid proteins.

Authors:  C R Merril; D Goldman; S A Sedman; M H Ebert
Journal:  Science       Date:  1981-03-27       Impact factor: 47.728

Review 5.  Drug and hormone effects on calcium release from bone.

Authors:  T J Martin
Journal:  Pharmacol Ther       Date:  1983       Impact factor: 12.310

6.  Receptors for 1,25(OH)2-vitamin D3 enriched in cloned osteoblast-like rat osteogenic sarcoma cells.

Authors:  N C Partridge; R J Frampton; J A Eisman; V P Michelangeli; E Elms; T R Bradley; T J Martin
Journal:  FEBS Lett       Date:  1980-06-16       Impact factor: 4.124

7.  Heparin modulates intracellular cyclic AMP in human trabecular bone cells and adherent rheumatoid synovial cells.

Authors:  A J Crisp; M S Roelke; S R Goldring; S M Krane
Journal:  Ann Rheum Dis       Date:  1984-08       Impact factor: 19.103

8.  Metabolic bone disease among in-patients with rheumatoid arthritis.

Authors:  B P Wordsworth; S Vipond; C G Woods; A G Mowat
Journal:  Br J Rheumatol       Date:  1984-11

9.  Biochemical characterization with parathormone and calcitonin of isolated bone cells: provisional identification of osteoclasts and osteoblasts.

Authors:  R A Luben; G L Wong; D V Cohn
Journal:  Endocrinology       Date:  1976-08       Impact factor: 4.736

10.  Functional properties of hormonally responsive cultured normal and malignant rat osteoblastic cells.

Authors:  N C Partridge; D Alcorn; V P Michelangeli; B E Kemp; G B Ryan; T J Martin
Journal:  Endocrinology       Date:  1981-01       Impact factor: 4.736
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