Literature DB >> 23169310

Surgical management of gallbladder disease in the very elderly: are we operating them at the right time?

Renato M Lupinacci1, Luis R Nadal, Ronaldo E Rego, André R Dias, Rafael S Marcari, Renato A Lupinacci, José F M Farah.   

Abstract

BACKGROUND: As life expectancy rises worldwide and the prevalence of gallstones increases with age, the number of very elderly patients requiring treatment for gallstone diseases is increasing. The aim of this study was to compare the results of cholecystectomy in patients 80 years or older according to different clinical presentations.
METHODS: This is a retrospective study of 81 patients 80 years or older. Indications for surgery were stratified into three groups: outpatients (symptomatic chronic cholecystitis), inpatients (complicated gallstone diseases), and urgent patients (acute cholecystitis). Data analysis included age, sex, the American Society of Anesthesiologists score, indication for surgery, length of hospital stay, morbidity, and mortality.
RESULTS: The mean age of the patients was 83.9 (range 80-94 years); there were 34 (42%) men. Thirty patients were operated on for acute cholecystitis. Patients in the urgency group significantly required the ICU more often, required a longer hospital stay, and had more complications, with 32% mortality. No differences were found between inpatients and outpatients, with both groups presenting low morbidity, no mortality, and the same postoperative length of stay.
CONCLUSION: More than 80% of the patients were operated on because of complicated gallstone disease. Although the outcomes of patients undergoing semielective cholecystectomy were similar to those of patients treated as outpatients, patients operated with acute cholecystitis presented extremely high morbidity and mortality rates. Thus, we can only recommend that early elective cholecystectomy be performed in elderly patients as soon as they are found to have symptomatic gallstones. Also, further trials are required to elucidate the optimal management of acute cholecystitis in elderly patients.

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Year:  2013        PMID: 23169310     DOI: 10.1097/MEG.0b013e32835b7124

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  13 in total

1.  The risk paradox: use of elective cholecystectomy in older patients is independent of their risk of developing complications.

Authors:  Taylor S Riall; Deepak Adhikari; Abhishek D Parmar; Suzanne K Linder; Francesca M Dimou; Winston Crowell; Nina P Tamirisa; Courtney M Townsend; James S Goodwin
Journal:  J Am Coll Surg       Date:  2014-12-17       Impact factor: 6.113

Review 2.  Laparoscopic cholecystectomy: consensus conference-based guidelines.

Authors:  Ferdinando Agresta; Fabio Cesare Campanile; Nereo Vettoretto; Gianfranco Silecchia; Carlo Bergamini; Pietro Maida; Pietro Lombari; Piero Narilli; Domenico Marchi; Alessandro Carrara; Maria Grazia Esposito; Stefania Fiume; Giuseppe Miranda; Simona Barlera; Marina Davoli
Journal:  Langenbecks Arch Surg       Date:  2015-04-08       Impact factor: 3.445

3.  Recurrence of biliary disease following non-operative management in elderly patients.

Authors:  Simon Bergman; Mohammed Al-Bader; Nadia Sourial; Isabelle Vedel; Wael C Hanna; Aaron J Bilek; Christos Galatas; Jonah E Marek; Shannon A Fraser
Journal:  Surg Endosc       Date:  2015-02-12       Impact factor: 4.584

4.  Determinants of variability in management of acute calculous cholecystitis.

Authors:  Philippe Paci; Nancy E Mayo; Pepa A Kaneva; Julio F Fiore; Gerald M Fried; Liane S Feldman
Journal:  Surg Endosc       Date:  2017-10-19       Impact factor: 4.584

5.  Trends in Follow-Up of Patients Presenting to the Emergency Department with Symptomatic Cholelithiasis.

Authors:  Francesca M Dimou; Deepak Adhikari; Hemalkumar B Mehta; Taylor S Riall
Journal:  J Am Coll Surg       Date:  2015-12-21       Impact factor: 6.113

6.  Protective and therapeutic experience of perioperative safety in extremely elderly patients with biliary diseases.

Authors:  Zongming Zhang; Yue Zhao; Fangcai Lin; Limin Liu; Chong Zhang; Zhuo Liu; Mingwen Zhu; Baijiang Wan; Hai Deng; Haiyan Yang; Lijun Jiao; Xiyuan Xie
Journal:  Medicine (Baltimore)       Date:  2021-05-28       Impact factor: 1.817

Review 7.  Acute cholecystitis: WSES position statement.

Authors:  Fabio Cesare Campanile; Michele Pisano; Federico Coccolini; Fausto Catena; Ferdinando Agresta; Luca Ansaloni
Journal:  World J Emerg Surg       Date:  2014-11-18       Impact factor: 5.469

Review 8.  2016 WSES guidelines on acute calculous cholecystitis.

Authors:  L Ansaloni; M Pisano; F Coccolini; A B Peitzmann; A Fingerhut; F Catena; F Agresta; A Allegri; I Bailey; Z J Balogh; C Bendinelli; W Biffl; L Bonavina; G Borzellino; F Brunetti; C C Burlew; G Camapanelli; F C Campanile; M Ceresoli; O Chiara; I Civil; R Coimbra; M De Moya; S Di Saverio; G P Fraga; S Gupta; J Kashuk; M D Kelly; V Koka; H Jeekel; R Latifi; A Leppaniemi; R V Maier; I Marzi; F Moore; D Piazzalunga; B Sakakushev; M Sartelli; T Scalea; P F Stahel; K Taviloglu; G Tugnoli; S Uraneus; G C Velmahos; I Wani; D G Weber; P Viale; M Sugrue; R Ivatury; Y Kluger; K S Gurusamy; E E Moore
Journal:  World J Emerg Surg       Date:  2016-06-14       Impact factor: 5.469

9.  Therapeutic experience of 289 elderly patients with biliary diseases.

Authors:  Zong-Ming Zhang; Zhuo Liu; Li-Min Liu; Chong Zhang; Hong-Wei Yu; Bai-Jiang Wan; Hai Deng; Ming-Wen Zhu; Zi-Xu Liu; Wen-Ping Wei; Meng-Meng Song; Yue Zhao
Journal:  World J Gastroenterol       Date:  2017-04-07       Impact factor: 5.742

10.  Conservative management of acute calculous cholecystitis complicated by pancreatitis in an elderly woman: A case report.

Authors:  Marta K Walczak-Galezewska; Damian Skrypnik; Monika Szulinska; Katarzyna Skrypnik; Pawel Bogdanski
Journal:  Medicine (Baltimore)       Date:  2018-06       Impact factor: 1.889

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