Tracheopathia osteochondroplastica: two unusual cases.

We describe 2 unusual cases of tracheopathia osteochondroplastica (TPO), one of them presenting with lung carcinoma and the other at an uncommon age. A 74-year-old man presented with chronic bronchitis and a left lower lobe lesion as detected on chest computed tomography. Flexible bronchoscopy revealed multiple calcified nodular lesions involving the anterior-lateral walls of the trachea and main bronchi. Histologic analysis of the tracheal nodules confirmed the presence of TPO. Squamous cell carcinoma was diagnosed by transthoracic needle aspiration of the pulmonary nodule. The relevance of coexistence of these 2 conditions remains unknown. Our second case was in a young man who presented with persistent cough and a chest computed tomography scan revealing multiple tracheal nodules. Numerous hard tracheal nodules distributed around the lower trachea and main bronchi were observed at flexible bronchoscopy. When the cough and dyspnea persists despite conventional empiric treatment, uncommon tracheobronchial pathologies, such as TPO, should be considered.