Endobronchial metastases from endometrial carcinoma.

A 78-year-old woman status post hysterectomy and radiation therapy 3 years earlier for endometrial carcinoma presented with cough, dyspnea, and weight loss. Computed tomography revealed left upper lobe atelectasis due to an obstructing endobronchial mass, enlarged mediastinal lymph nodes, a moderate left pleural effusion, and several subcentimeter nodules in the right lung. Flexible bronchoscopy confirmed a tumor mass obstructing the left upper lobe bronchus. Endobronchial biopsy revealed metastatic adenocarcinoma with histology similar to the previously resected endometrial primary and immunohistochemical staining consistent with endometrial carcinoma. To our knowledge, endobronchial metastases from endometrial carcinoma have been reported only once before.