Geir Selbæk1, Knut Engedal, Sverre Bergh. 1. Department for Research and Development, Division of Mental Health Services, Centre for Old Age Psychiatric Research, Innlandet Hospital Trust, Ottestad, Norway. geir.selbaek@aldringoghelse.no
Abstract
BACKGROUND: Persons with dementia frequently exhibit neuropsychiatric symptoms (NPSs). Previous studies have indicated that the prevalence is particularly high in nursing home (NH) patients. However, differences in methodology in studies of the prevalence and course of NPSs have made it difficult to compare their results. METHODS: We searched the electronic databases MEDLINE, EMBASE, PsycINFO, Ovid Nursing, and AgeLine from their inception until July 2012 using medical subject headings to identify studies that reported figures on the prevalence and course of NPSs in NH patients with dementia. RESULTS: A total of 28 studies met the inclusion criteria. In total, 8468 and 1458 persons participated in the prevalence and longitudinal studies, respectively. The weighted mean prevalence of having at least one NPS was 82%. Although the prevalence of individual symptoms varied, the highest prevalence figures were found for agitation and apathy. The persistence of individual NPSs varied substantially, but in these studies, having at least one NPS was highly persistent across the studies. CONCLUSION: This review confirms that clinically significant NPSs are common in NH patients with dementia. Even though great variability exists across studies, recent studies applying similar methodology have made comparisons between studies feasible, revealing relatively consistent prevalence patterns for individual symptoms. The natural course of symptoms deserves closer attention. This is vital in planning prevention and treatment of NPSs in NH patients with dementia.
BACKGROUND:Persons with dementia frequently exhibit neuropsychiatric symptoms (NPSs). Previous studies have indicated that the prevalence is particularly high in nursing home (NH) patients. However, differences in methodology in studies of the prevalence and course of NPSs have made it difficult to compare their results. METHODS: We searched the electronic databases MEDLINE, EMBASE, PsycINFO, Ovid Nursing, and AgeLine from their inception until July 2012 using medical subject headings to identify studies that reported figures on the prevalence and course of NPSs in NHpatients with dementia. RESULTS: A total of 28 studies met the inclusion criteria. In total, 8468 and 1458 persons participated in the prevalence and longitudinal studies, respectively. The weighted mean prevalence of having at least one NPS was 82%. Although the prevalence of individual symptoms varied, the highest prevalence figures were found for agitation and apathy. The persistence of individual NPSs varied substantially, but in these studies, having at least one NPS was highly persistent across the studies. CONCLUSION: This review confirms that clinically significant NPSs are common in NHpatients with dementia. Even though great variability exists across studies, recent studies applying similar methodology have made comparisons between studies feasible, revealing relatively consistent prevalence patterns for individual symptoms. The natural course of symptoms deserves closer attention. This is vital in planning prevention and treatment of NPSs in NHpatients with dementia.
Authors: Justine S Sefcik; Caroline Madrigal; Allison R Heid; Sheila L Molony; Kimberly Van Haitsma; Irene Best; Barbara Resnick; Elizabeth Galik; Marie Boltz; Ann Kolanowski Journal: J Gerontol Nurs Date: 2020-11-01 Impact factor: 1.254
Authors: Alyssa N De Vito; Matthew Calamia; Daniel S Weitzner; John P K Bernstein Journal: Int J Geriatr Psychiatry Date: 2018-10-01 Impact factor: 3.485
Authors: Stephen E Gordon; Alyssa B Dufour; Sara M Monti; Melissa L P Mattison; Angela G Catic; Cindy P Thomas; Lewis A Lipsitz Journal: J Am Med Dir Assoc Date: 2016-05-06 Impact factor: 4.669
Authors: Claudia M Groot Kormelinck; Charlotte F van Teunenbroek; Sytse U Zuidema; Martin Smalbrugge; Debby L Gerritsen Journal: BMC Geriatr Date: 2021-07-03 Impact factor: 3.921