Literature DB >> 23166049

Evaluation of cell function upon nanovector internalization.

Jonathan O Martinez1, Alessandro Parodi, Xuewu Liu, Mikhail G Kolonin, Mauro Ferrari, Ennio Tasciotti.   

Abstract

In vitro toxicity assays based on the evaluation and retention of advanced and specific cellular functions are proposed to investigate mesoporous silicon nanovectors. This approach provides greater insight compared to simple cellular viability and toxicity assays. Electron microscopy images demonstrate internalized nanovectors altering the curvature of the nuclear envelope with minimal effect on viability or biological function.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 23166049      PMCID： PMC3733230          DOI： 10.1002/smll.201202001

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  38 in total

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6.  Tailored porous silicon microparticles: fabrication and properties.

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Journal:  Chemphyschem       Date:  2010-04-06       Impact factor: 3.102

7.  Failure of MTT as a toxicity testing agent for mesoporous silicon microparticles.

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Review 8.  Antibiological barrier nanovector technology for cancer applications.

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Review 10.  Nanocarriers as an emerging platform for cancer therapy.

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  9 in total

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2.  Degradation and biocompatibility of multistage nanovectors in physiological systems.

Authors:  Jonathan O Martinez; Michael Evangelopoulos; Ciro Chiappini; Xuewu Liu; Mauro Ferrari; Ennio Tasciotti
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5.  Chlorin e6 Functionalized Theranostic Multistage Nanovectors Transported by Stem Cells for Effective Photodynamic Therapy.

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6.  A specifically designed nanoconstruct associates, internalizes, traffics in cardiovascular cells, and accumulates in failing myocardium: a new strategy for heart failure diagnostics and therapeutics.

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Journal:  Biomaterials       Date:  2015-12-02       Impact factor: 12.479

9.  Thermally responsive hydrogel for atrial fibrillation related stroke prevention.

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  9 in total

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