Literature DB >> 23166020

Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes.

Chun Kit Kwok1, Madeline E Sherlock, Philip C Bevilacqua.   

Abstract

Keeping a broad (RNA) perspective: conventional biochemical detection systems only have a 100-fold linear response range. The range of potassium concentrations detected by an RNA G-quadruplex sequence can be broadened by intentionally populating multiple intermediate folding states. The folding of the RNA G-quadruplexes was monitored by both circular dichroism and intrinsic fluorescence spectroscopy.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID: 23166020     DOI: 10.1002/anie.201206475

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  7 in total

1.  Using the population-shift mechanism to rationally introduce "Hill-type" cooperativity into a normally non-cooperative receptor.

Authors:  Anna J Simon; Alexis Vallée-Bélisle; Francesco Ricci; Herschel M Watkins; Kevin W Plaxco
Journal:  Angew Chem Int Ed Engl       Date:  2014-07-11       Impact factor: 15.336

2.  Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors.

Authors:  Anna J Simon; Alexis Vallée-Bélisle; Francesco Ricci; Kevin W Plaxco
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-06       Impact factor: 11.205

3.  Multimerization rules for G-quadruplexes.

Authors:  Sofia Kolesnikova; Martin Hubálek; Lucie Bednárová; Josef Cvacka; Edward A Curtis
Journal:  Nucleic Acids Res       Date:  2017-09-06       Impact factor: 16.971

4.  Targeted Detection of G-Quadruplexes in Cellular RNAs.

Authors:  Chun Kit Kwok; Shankar Balasubramanian
Journal:  Angew Chem Int Ed Engl       Date:  2015-04-23       Impact factor: 15.336

5.  Molecular crowders and cosolutes promote folding cooperativity of RNA under physiological ionic conditions.

Authors:  Christopher A Strulson; Joshua A Boyer; Elisabeth E Whitman; Philip C Bevilacqua
Journal:  RNA       Date:  2014-01-17       Impact factor: 4.942

6.  Spectroscopic analysis reveals the effect of hairpin loop formation on G-quadruplex structures.

Authors:  Hengxin Feng; Chun Kit Kwok
Journal:  RSC Chem Biol       Date:  2022-03-10

7.  Amyloid Precursor Protein Translation Is Regulated by a 3'UTR Guanine Quadruplex.

Authors:  Ezekiel Crenshaw; Brian P Leung; Chun Kit Kwok; Michal Sharoni; Kalee Olson; Neeraj P Sebastian; Sara Ansaloni; Reinhard Schweitzer-Stenner; Michael R Akins; Philip C Bevilacqua; Aleister J Saunders
Journal:  PLoS One       Date:  2015-11-30       Impact factor: 3.240

  7 in total

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