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Literature DB >> 23164954

High signal contrast gating with biomodified Gd doped mesoporous nanoparticles.

Wen-Yen Huang¹, Gemma-Louise Davies, Jason J Davis.

Abstract

Internally Gd doped mesoporous nanoparticles have been prepared and exhibit unprecedented relaxivities that are retained on external biomodification. In tuning diffusive water access, image contrast can be reversibly switched in the presence of a specific protein target.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2012 PMID： 23164954 PMCID： PMC4454276 DOI： 10.1039/c2cc37545a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

34 in total

1. Enzyme-Activated Gd(3+) Magnetic Resonance Imaging Contrast Agents with a Prominent Receptor-Induced Magnetization Enhancement We thank Dr. Shrikumar Nair for helpful discussions.

Authors: Alexander L. Nivorozhkin; Andrew F. Kolodziej; Peter Caravan; Matthew T. Greenfield; Randall B. Lauffer; Thomas J. McMurry
Journal: Angew Chem Int Ed Engl Date: 2001-08-03 Impact factor: 15.336

2. Magnetic resonance imaging detects a specific peptide-protein binding event.

Authors: Luis M De León-Rodríguez; Alfonso Ortiz; Allison L Weiner; Shanrong Zhang; Zoltan Kovacs; Thomas Kodadek; A Dean Sherry
Journal: J Am Chem Soc Date: 2002-04-10 Impact factor: 15.419

3. Enhancement of the water proton relaxivity by trapping Gd3+ complexes in nanovesicles.

Authors: Pascal H Fries; Elie Belorizky
Journal: J Chem Phys Date: 2010-07-14 Impact factor: 3.488

4. The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform.

Authors: Seungpyo Hong; Pascale R Leroueil; István J Majoros; Bradford G Orr; James R Baker; Mark M Banaszak Holl
Journal: Chem Biol Date: 2007-01

5. Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery.

Authors: Zhong Luo; Kaiyong Cai; Yan Hu; Li Zhao; Peng Liu; Lin Duan; Weihu Yang
Journal: Angew Chem Int Ed Engl Date: 2010-12-09 Impact factor: 15.336

6. The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates.

Authors: Peter Caravan; Normand J Cloutier; Matthew T Greenfield; Sarah A McDermid; Stephen U Dunham; Jeff W M Bulte; John C Amedio; Richard J Looby; Ronald M Supkowski; William DeW Horrocks; Thomas J McMurry; Randall B Lauffer
Journal: J Am Chem Soc Date: 2002-03-27 Impact factor: 15.419

7. pH-dependent modulation of relaxivity and luminescence in macrocyclic gadolinium and europium complexes based on reversible intramolecular sulfonamide ligation.

Authors: M P Lowe; D Parker; O Reany; S Aime; M Botta; G Castellano; E Gianolio; R Pagliarin
Journal: J Am Chem Soc Date: 2001-08-08 Impact factor: 15.419

8. Multimodality and nanoparticles in medical imaging.

Authors: Wen-Yen Huang; Jason J Davis
Journal: Dalton Trans Date: 2011-03-14 Impact factor: 4.390

9. Effect of DOTA position on melanoma targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide.

Authors: Haixun Guo; Jianquan Yang; Fabio Gallazzi; Eric R Prossnitz; Larry A Sklar; Yubin Miao
Journal: Bioconjug Chem Date: 2009-11 Impact factor: 4.774

High signal contrast gating with biomodified Gd doped mesoporous nanoparticles.

1. Enzyme-Activated Gd(3+) Magnetic Resonance Imaging Contrast Agents with a Prominent Receptor-Induced Magnetization Enhancement We thank Dr. Shrikumar Nair for helpful discussions.

2. Magnetic resonance imaging detects a specific peptide-protein binding event.

3. Enhancement of the water proton relaxivity by trapping Gd3+ complexes in nanovesicles.

4. The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform.

5. Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery.

6. The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates.

7. pH-dependent modulation of relaxivity and luminescence in macrocyclic gadolinium and europium complexes based on reversible intramolecular sulfonamide ligation.

8. Multimodality and nanoparticles in medical imaging.

9. Effect of DOTA position on melanoma targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide.

10. Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase.

1. Non-covalent self assembly controls the relaxivity of magnetically active guests.

Review 2. Environmentally responsive MRI contrast agents.

3. Engineering cytochrome-modified silica nanoparticles to induce programmed cell death.

Review 4. Nanoparticle-Based Paramagnetic Contrast Agents for Magnetic Resonance Imaging.

Review 5. Magnetic Nanoparticles Supporting Bio-responsive T₁/T₂ Magnetic Resonance Imaging.

Review 2. Environmentally responsive MRI contrast agents.

Review 4. Nanoparticle-Based Paramagnetic Contrast Agents for Magnetic Resonance Imaging.

Review 5. Magnetic Nanoparticles Supporting Bio-responsive T1/T2 Magnetic Resonance Imaging.

Review 5. Magnetic Nanoparticles Supporting Bio-responsive T₁/T₂ Magnetic Resonance Imaging.