Literature DB >> 23164903

Whispering gallery mode laser based on antitumor drug-dye complex gain medium.

Fernando Lahoz1, Claudio J Oton, David López, Jorge Marrero-Alonso, Alicia Boto, Mario Díaz.   

Abstract

Optofluidic lasers have emerged as a new research field over the past few years. Most frequently they use conventional dye molecules as the gain medium. In this Letter, we demonstrate a laser emission produced by the coupling of the evanescent whispering gallery modes that resonate in a cylindrical microresonator to a newly developed gain medium. This medium is formed by attachment of a 7-nitrobenzo [c] [1,2,5]-oxadiazol-4-yl fluorescent tag to tamoxifen, the most widely used drug in the treatment of breast cancer. The antitumor character of the gain medium paves the way to novel biophotonic applications.

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Year:  2012        PMID: 23164903     DOI: 10.1364/ol.37.004756

Source DB:  PubMed          Journal:  Opt Lett        ISSN: 0146-9592            Impact factor:   3.776


  2 in total

1.  A fiber-tip label-free biological sensing platform: a practical approach toward in-vivo sensing.

Authors:  Alexandre François; Tess Reynolds; Tanya M Monro
Journal:  Sensors (Basel)       Date:  2015-01-09       Impact factor: 3.576

2.  FLTX2: A Novel Tamoxifen Derivative Endowed with Antiestrogenic, Fluorescent, and Photosensitizer Properties.

Authors:  Mario Díaz; Fernando Lobo; Dácil Hernández; Ángel Amesty; Catalina Valdés-Baizabal; Ana Canerina-Amaro; Fátima Mesa-Herrera; Kevin Soler; Alicia Boto; Raquel Marín; Ana Estévez-Braun; Fernando Lahoz
Journal:  Int J Mol Sci       Date:  2021-05-19       Impact factor: 5.923

  2 in total

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