BACKGROUND: The aim of this study was to discuss the possibility of mean platelet volume (MPV) being a new risk factor in the etiology of portal venous thrombosis (PVT). METHODS: Study participants were categorized into 2 different groups: group I, control group (n = 35) and group II, PVT group (n = 34). Demographic data and MPV values were recorded retrospectively. RESULTS: No differences were determined between the 2 groups regarding hypertension, diabetes mellitus, and smoking (P > .05). The average hemoglobin levels were 10.8 ± 2.1 in group II and 14.0 ± 1.7 in group I (P < .001). Although the MPV levels of group II patients were 8.2 ± 0.52, the average level in group I was determined as 7.8 ± 0.62 (P = .012). In the performed receiver-operating characteristic (ROC) analysis, the cutoff value for patients with PVT for MPV was determined as 7.9 (area under curve: 0.674), sensitivity as 70.6%, and specificity as 65.7% (P = .013). CONCLUSION: The current study shows that MPV is significantly higher in patients with PVT than in the control group.
BACKGROUND: The aim of this study was to discuss the possibility of mean platelet volume (MPV) being a new risk factor in the etiology of portal venous thrombosis (PVT). METHODS: Study participants were categorized into 2 different groups: group I, control group (n = 35) and group II, PVT group (n = 34). Demographic data and MPV values were recorded retrospectively. RESULTS: No differences were determined between the 2 groups regarding hypertension, diabetes mellitus, and smoking (P > .05). The average hemoglobin levels were 10.8 ± 2.1 in group II and 14.0 ± 1.7 in group I (P < .001). Although the MPV levels of group II patients were 8.2 ± 0.52, the average level in group I was determined as 7.8 ± 0.62 (P = .012). In the performed receiver-operating characteristic (ROC) analysis, the cutoff value for patients with PVT for MPV was determined as 7.9 (area under curve: 0.674), sensitivity as 70.6%, and specificity as 65.7% (P = .013). CONCLUSION: The current study shows that MPV is significantly higher in patients with PVT than in the control group.
Entities:
Keywords:
etiology; mean platelet volume; portal venous thrombosis
Authors: Jun Yang; Xuan Zhou; Xiaorong Fan; Min Xiao; Dinghua Yang; Bo Liang; Meng Dai; Lanlan Shan; Jingbo Lu; Zhiqi Lin; Rong Liu; Jun Liu; Liping Wang; Mei Zhong; Yu Jiang; Xiaochun Bai Journal: Blood Date: 2016-06-10 Impact factor: 22.113