Literature DB >> 23161356

Psychological impact of unexpected explicit recall of events occurring during surgery performed under sedation, regional anaesthesia, and general anaesthesia: data from the Anesthesia Awareness Registry.

C D Kent1, G A Mashour, N A Metzger, K L Posner, K B Domino.   

Abstract

BACKGROUND: Anaesthetic awareness is a recognized complication of general anaesthesia (GA) and is associated with post-traumatic stress disorder (PTSD). Although complete amnesia for intraprocedural events during sedation and regional anaesthesia (RA) may occur, explicit recall is expected by anaesthesia providers. Consequently, the possibility that there could be psychological consequences associated with unexpected explicit recall of events during sedation and RA has not been investigated. This study investigated the psychological sequelae of unexpected explicit recall of events during sedation/RA that was reported to the Anesthesia Awareness Registry.
METHODS: The Registry recruited subjects who self-identified as having had anaesthetic awareness. Inclusion criteria were a patient-reported awareness experience in 1990 or later and availability of medical records. The sensations experienced by the subjects during their procedure and the acute and persistent psychological sequelae attributed to this explicit recall were assessed for patients receiving sedation/RA and those receiving GA.
RESULTS: Among the patients fulfilling the inclusion criteria, medical record review identified 27 sedation/RA and 50 GA cases. Most patients experienced distress (78% of sedation/RA vs 94% of GA). Approximately 40% of patients with sedation/RA had persistent psychological sequelae, similar to GA patients. Some sedation/RA patients reported an adverse impact on their job performance (15%), family relationships (11%), and friendships (11%), and 15% reported being diagnosed with PTSD.
CONCLUSIONS: Patients who self-reported to the Registry unexpected explicit recall of events during sedation/RA experienced distress and persistent psychological sequelae comparable with those who had reported anaesthetic awareness during GA. Further study is warranted to determine if patients reporting distress with explicit recall after sedation/RA require psychiatric follow-up.

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Year:  2012        PMID: 23161356     DOI: 10.1093/bja/aes386

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  6 in total

Review 1.  Anesthesia and the neurobiology of fear and posttraumatic stress disorder.

Authors:  Keith M Vogt; Kane O Pryor
Journal:  Curr Opin Anaesthesiol       Date:  2022-08-19       Impact factor: 2.733

Review 2.  Complexities of human memory: relevance to anaesthetic practice.

Authors:  R A Veselis
Journal:  Br J Anaesth       Date:  2018-07       Impact factor: 9.166

3.  Identifying Recall Under Sedation by a Novel EEG Based Index of Attention-A Pilot Study.

Authors:  Dana Baron Shahaf; Avi Weissman; Leonid Priven; Goded Shahaf
Journal:  Front Med (Lausanne)       Date:  2022-04-14

4.  Influence of Isoflurane on Immediate-Early Gene Expression.

Authors:  Kristopher M Bunting; Rebecca I Nalloor; Almira Vazdarjanova
Journal:  Front Behav Neurosci       Date:  2016-01-12       Impact factor: 3.558

5.  The Impact of Endoscopy Sedation Information Sheets on the Level of Concern Regarding Possible Awareness in Patients Undergoing Endoscopy Sedation.

Authors:  Zi Ping Tong; Lincoln Gan Lim; Alison Pighills; Matthew Hiskens; Danny Bartlett
Journal:  Healthcare (Basel)       Date:  2021-12-24

6.  Anesthetic dreaming, anesthesia awareness and patient satisfaction after deep sedation with propofol target controlled infusion: A prospective cohort study of patients undergoing day case breast surgery.

Authors:  Marco Cascella; Roberta Fusco; Domenico Caliendo; Vincenza Granata; Domenico Carbone; Maria Rosaria Muzio; Giuseppe Laurelli; Stefano Greggi; Francesca Falcone; Cira Antonietta Forte; Arturo Cuomo
Journal:  Oncotarget       Date:  2017-04-19
  6 in total

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