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Literature DB >> 23161205

Cell polarity and cystic kidney disease.

Abstract

Epithelial cell polarity is essential for organ development; aberrations in this process have been implicated in various diseases, including polycystic kidney disease. Establishment and maintenance of cell polarity is governed by a number of molecular processes and how these processes operate remains an interesting question. Conserved protein complexes guide both apical-basolateral polarity and planar cell polarity. In this review we discuss the recent findings that provide insights into polarity mechanisms and the intriguing crosstalk between apical-basolateral polarity and planar cell polarity, and their relationship to cystic kidney disease.

Entities: Disease

Mesh：

Year: 2012 PMID： 23161205 DOI： 10.1007/s00467-012-2337-z

Source DB: PubMed Journal: Pediatr Nephrol ISSN： 0931-041X Impact factor: 3.714

110 in total

1. Molecular cloning and characterization of Pals, proteins associated with mLin-7.

Authors: E Kamberov; O Makarova; M Roh; A Liu; D Karnak; S Straight; B Margolis
Journal: J Biol Chem Date: 2000-04-14 Impact factor: 5.157

2. Identification of Vangl2 and Scrb1 as planar polarity genes in mammals.

Authors: Mireille Montcouquiol; Rivka A Rachel; Pamela J Lanford; Neal G Copeland; Nancy A Jenkins; Matthew W Kelley
Journal: Nature Date: 2003-04-30 Impact factor: 49.962

3. Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia.

Authors: Antonia Borovina; Simone Superina; Daniel Voskas; Brian Ciruna
Journal: Nat Cell Biol Date: 2010-03-21 Impact factor: 28.824

4. Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals.

Authors: Mireille Montcouquiol; Nathalie Sans; David Huss; Jacob Kach; J David Dickman; Andrew Forge; Rivka A Rachel; Neal G Copeland; Nancy A Jenkins; Debora Bogani; Jennifer Murdoch; Mark E Warchol; Robert J Wenthold; Matthew W Kelley
Journal: J Neurosci Date: 2006-05-10 Impact factor: 6.167

5. Impaired formation of desmosomal junctions in ADPKD epithelia.

Authors: Ryan J Russo; Hervé Husson; Dominique Joly; Nikolay O Bukanov; Natacha Patey; Bertrand Knebelmann; Oxana Ibraghimov-Beskrovnaya
Journal: Histochem Cell Biol Date: 2005-09-27 Impact factor: 4.304

Review 6. The Scribble and Par complexes in polarity and migration: friends or foes?

Authors: Patrick O Humbert; Lukas E Dow; Sarah M Russell
Journal: Trends Cell Biol Date: 2006-10-25 Impact factor: 20.808

7. Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins.

Authors: Y Huan; J van Adelsberg
Journal: J Clin Invest Date: 1999-11 Impact factor: 14.808

8. Asymmetrically distributed PAR-3 protein contributes to cell polarity and spindle alignment in early C. elegans embryos.

Authors: B Etemad-Moghadam; S Guo; K J Kemphues
Journal: Cell Date: 1995-12-01 Impact factor: 41.582

9. CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells.

Authors: Céline Lemmers; Didier Michel; Lydie Lane-Guermonprez; Marie-Hélène Delgrossi; Emmanuelle Médina; Jean-Pierre Arsanto; André Le Bivic
Journal: Mol Biol Cell Date: 2004-01-12 Impact factor: 4.138

10. Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice.

Authors: Olav Olsen; Lars Funke; Jia-fu Long; Masaki Fukata; Toshinari Kazuta; Jonathan C Trinidad; Kimberly A Moore; Hidemi Misawa; Paul A Welling; Alma L Burlingame; Mingjie Zhang; David S Bredt
Journal: J Cell Biol Date: 2007-10-08 Impact factor: 10.539

10 in total

Review 1. The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease.

Authors: Tamina Seeger-Nukpezah; Daniel M Geynisman; Anna S Nikonova; Thomas Benzing; Erica A Golemis
Journal: Nat Rev Nephrol Date: 2015-04-14 Impact factor: 28.314

Review 2. A holey pursuit: lumen formation in the developing kidney.

Authors: Denise K Marciano
Journal: Pediatr Nephrol Date: 2016-02-22 Impact factor: 3.714

3. The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane.

Authors: Wenyan Xu; Miaomiao Jin; Ruikun Hu; Hong Wang; Fan Zhang; Shiaulou Yuan; Ying Cao
Journal: J Am Soc Nephrol Date: 2016-07-08 Impact factor: 10.121

4. Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney.

Authors: Bo Zhang; Uyen Tran; Oliver Wessely
Journal: Development Date: 2018-03-22 Impact factor: 6.868

Review 5. Polycystin-1: a master regulator of intersecting cystic pathways.

Authors: Sorin V Fedeles; Anna-Rachel Gallagher; Stefan Somlo
Journal: Trends Mol Med Date: 2014-01-31 Impact factor: 11.951

6. Crumbs3 is essential for proper epithelial development and viability.

Authors: Eileen L Whiteman; Shuling Fan; Jennifer L Harder; Katherine D Walton; Chia-Jen Liu; Abdul Soofi; Vanessa C Fogg; Marc B Hershenson; Gregory R Dressler; Gail H Deutsch; Deborah L Gumucio; Ben Margolis
Journal: Mol Cell Biol Date: 2013-10-28 Impact factor: 4.272