| Literature DB >> 2316002 |
I A Shulman1, P A Arndt, W McGehee, G Garratty.
Abstract
Until recently, all cephalosporin-induced immune hemolytic anemias appeared to react by a "penicillin-type" drug adsorption mechanism, and hemolysis was extravascular. In 1987 and 1988, the first two cases of cephalosporin-induced immune hemolytic anemia with intravascular hemolysis associated with a so-called immune complex mechanism were reported. This report describes a case of extravascular hemolysis due to a third-generation cephalosporin, cefotaxime, which, to the authors' knowledge, is the first to show in vitro characteristics of both the drug adsorption and the so-called immune complex mechanisms.Entities:
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Year: 1990 PMID： 2316002 DOI： 10.1046/j.1537-2995.1990.30390194351.x
Source DB: PubMed Journal: Transfusion ISSN： 0041-1132 Impact factor: 3.157