BACKGROUND AND AIMS: Global population aging has been one of the defining processes of the twentieth century, with profound economic, political and social consequences. It is driving the current epidemic of dementia, both in terms of its extent and global distribution. The aim of the study was to summarize recent findings relevant to the epidemiological knowledge of dementia and Alzheimer's disease (AD). METHODS: A narrative mini-review of the literature relevant to the epidemiology of dementia and AD is presented, summarizing important findings and analyzing their implications. RESULTS: It was estimated that in 2010 there were 36.5 million people living with dementia, with 7.7 million new cases yearly and a new case of dementia every 4 sec. The number of persons living with dementia will nearly double every 20 years. Most of these persons will be living in low- and middle-income countries (LMIC). CONCLUSIONS: There are a substantial number of people with dementia worldwide and these numbers will continue to increase mainly in LMIC, producing a wide range of impacts. It is important to make dementia a national public health and social care priority worldwide. Recent reviews and meta-analyses have failed to clearly identify a singular causal or preventive pathway for AD that seems to be a multicausal, heterogeneous and age-related condition.
BACKGROUND AND AIMS: Global population aging has been one of the defining processes of the twentieth century, with profound economic, political and social consequences. It is driving the current epidemic of dementia, both in terms of its extent and global distribution. The aim of the study was to summarize recent findings relevant to the epidemiological knowledge of dementia and Alzheimer's disease (AD). METHODS: A narrative mini-review of the literature relevant to the epidemiology of dementia and AD is presented, summarizing important findings and analyzing their implications. RESULTS: It was estimated that in 2010 there were 36.5 million people living with dementia, with 7.7 million new cases yearly and a new case of dementia every 4 sec. The number of persons living with dementia will nearly double every 20 years. Most of these persons will be living in low- and middle-income countries (LMIC). CONCLUSIONS: There are a substantial number of people with dementia worldwide and these numbers will continue to increase mainly in LMIC, producing a wide range of impacts. It is important to make dementia a national public health and social care priority worldwide. Recent reviews and meta-analyses have failed to clearly identify a singular causal or preventive pathway for AD that seems to be a multicausal, heterogeneous and age-related condition.
Authors: Brandon E Gavett; Vanessa Vudy; Mary Jeffrey; Samantha E John; Ashita S Gurnani; Jason W Adams Journal: Neuropsychology Date: 2014-08-25 Impact factor: 3.295
Authors: Chris Fox; Ian Maidment; Esme Moniz-Cook; Jacquie White; Jochen René Thyrian; John Young; Cornelius Katona; Carolyn A Chew-Graham Journal: Ment Health Fam Med Date: 2013-09
Authors: Alessandro Biffi; Mert R Sabuncu; Rahul S Desikan; Nick Schmansky; David H Salat; Jonathan Rosand; Christopher D Anderson Journal: Neurobiol Aging Date: 2014-02-05 Impact factor: 4.673
Authors: Roy Lardenoije; Daniël L A van den Hove; Monique Havermans; Anne van Casteren; Kevin X Le; Roberta Palmour; Cynthia A Lemere; Bart P F Rutten Journal: Mol Cell Neurosci Date: 2017-11-04 Impact factor: 4.314