Literature DB >> 23158401

Data management in thrombin generation.

H Coenraad Hemker1, R Kremers.   

Abstract

To obtain a thrombin generation (TG) curve from the conversion of added fluorogenic substrate, thrombin concentrations are to be derived from the observed velocity of increase of fluorescence (dF/dt). The relation between velocity and thrombin concentration varies during the experiment because substrate is consumed and because fluorescence is not linear with the concentration of product. Here we review the techniques that we developed to:
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 23158401     DOI： 10.1016/j.thromres.2012.10.011

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   3.944


  37 in total

1.  Re-evaluation of mouse tissue factor pathway inhibitor and comparison of mouse and human tissue factor pathway inhibitor physiology.

Authors:  T J Girard; K Grunz; N M Lasky; J P Malone; G J Broze
Journal:  J Thromb Haemost       Date:  2018-10-22       Impact factor: 5.824

2.  Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo.

Authors:  Jevgenia Zilberman-Rudenko; Hiroshi Deguchi; Meenal Shukla; Yoshimasa Oyama; Jennifer N Orje; Zihan Guo; Tine Wyseure; Laurent O Mosnier; Owen J T McCarty; Zaverio M Ruggeri; Tobias Eckle; John H Griffin
Journal:  Arterioscler Thromb Vasc Biol       Date:  2020-02-27       Impact factor: 8.311

3.  Direct Amplification of Tissue Factor:Factor VIIa Procoagulant Activity by Bile Acids Drives Intrahepatic Coagulation.

Authors:  Kevin S Baker; Anna K Kopec; Asmita Pant; Lauren G Poole; Holly Cline-Fedewa; Dora Ivkovich; Mojtaba Olyaee; Benjamin L Woolbright; Adam Miszta; Hartmut Jaeschke; Alisa S Wolberg; James P Luyendyk
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-08-15       Impact factor: 8.311

4.  Proposal for standardized preanalytical and analytical conditions for measuring thrombin generation in hemophilia: communication from the SSC of the ISTH.

Authors:  Y Dargaud; A S Wolberg; E Gray; C Negrier; H C Hemker
Journal:  J Thromb Haemost       Date:  2017-06-28       Impact factor: 5.824

5.  Suppressing protein Z-dependent inhibition of factor Xa improves coagulation in hemophilia A.

Authors:  T J Girard; N M Lasky; K Grunz; G J Broze
Journal:  J Thromb Haemost       Date:  2018-12-16       Impact factor: 5.824

6.  Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va.

Authors:  Hiroshi Deguchi; Ranjeet K Sinha; Patrizia Marchese; Zaverio M Ruggeri; Jevgenia Zilberman-Rudenko; Owen J T McCarty; Mitchell J Cohen; John H Griffin
Journal:  Blood       Date:  2016-07-15       Impact factor: 22.113

7.  Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin.

Authors:  Romy M W Kremers; Stéphane Zuily; Hilde Kelchtermans; Tessa C Peters; Saartje Bloemen; Véronique Regnault; H Coenraad Hemker; Philip G de Groot; Denis Wahl; Bas de Laat
Journal:  Blood Adv       Date:  2018-06-12

8.  A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice.

Authors:  Adam Miszta; Anna K Kopec; Asmita Pant; Lori A Holle; James R Byrnes; Daniel A Lawrence; Kirk C Hansen; Matthew J Flick; James P Luyendyk; Bas de Laat; Alisa S Wolberg
Journal:  Blood       Date:  2020-05-07       Impact factor: 22.113

9.  Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery.

Authors:  Adam Miszta; Homa K Ahmadzia; Naomi L C Luban; Shuhui Li; Dong Guo; Lori A Holle; Jeffrey S Berger; Andra H James; Jogarao V S Gobburu; John van den Anker; Bas de Laat; Alisa S Wolberg
Journal:  J Thromb Haemost       Date:  2020-12-26       Impact factor: 5.824

10.  Thrombin Generation as a Method to Identify the Risk of Bleeding in High Clinical-Risk Patients Using Dual Antiplatelet Therapy.

Authors:  C P D M de Breet; S Zwaveling; M J A Vries; R G van Oerle; Y M C Henskens; A W J Van't Hof; P E J van der Meijden; L Veenstra; H Ten Cate; R H Olie
Journal:  Front Cardiovasc Med       Date:  2021-06-10
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