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Literature DB >> 23153529

PGAMgnam style: a glycolytic switch controls biosynthesis.

Abstract

Therapeutic strategies that target glycolysis and biosynthetic pathways in cancer cells are currently the main focus of research in the field of cancer metabolism. In this issue of Cancer Cell, Hitosugi and colleagues show that targeting PGAM1 could be a way of "killing two birds with one stone".

Entities: Disease Gene

Year: 2012 PMID： 23153529 DOI： 10.1016/j.ccr.2012.10.014

Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743

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Cited

8 in total

Review 1. Regulation of tumor metabolism by post translational modifications on metabolic enzymes.

Authors: Abhisha Sawant Dessai; Poonam Kalhotra; Aaron T Novickis; Subhamoy Dasgupta
Journal: Cancer Gene Ther Date: 2022-08-23 Impact factor: 5.854

2. An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma.

Authors: Chen-Lei Wen; Ke Huang; Lu-Lu Jiang; Xiong-Xiong Lu; Yu-Ting Dai; Min-Min Shi; Xiao-Mei Tang; Qing-Bing Wang; Xiao-Dan Zhang; Peng-Hui Wang; Hui-Ti Li; Xiao-Xue Ruan; Li-Wen Wang; Xin-Jing Wang; Qian Wang; Wei Lu; Xiao-Qiang Xiang; Xun Sun; Yan-Hui Xu; Lu-Hua Lai; Qian Zhan; Hong-Wei Li; Cheng-Hong Peng; Jing Chen; Jin-Yan Huang; De-Yong Ye; Sai-Juan Chen; Zhu Chen; Min Li; Yuan Fang; Bai-Yong Shen; Lu Zhou
Journal: Proc Natl Acad Sci U S A Date: 2019-10-29 Impact factor: 11.205

3. Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.

Authors: Guang Yang; Ying Yuan; Hongfeng Yuan; Jiapei Wang; Haolin Yun; Yu Geng; Man Zhao; Linhan Li; Yejing Weng; Zixian Liu; Jinyan Feng; Yanan Bu; Lei Liu; Bingnan Wang; Xiaodong Zhang
Journal: EMBO Rep Date: 2020-12-29 Impact factor: 8.807

4. Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion.

Authors: Yao-An Wen; Bo-Wei Zhou; Dao-Jun Lv; Fang-Peng Shu; Xian-Lu Song; Bin Huang; Chong Wang; Shan-Chao Zhao
Journal: Asian J Androl Date: 2018 Mar-Apr Impact factor: 3.285

5. Phosphoglyceric acid mutase-1 contributes to oncogenic mTOR-mediated tumor growth and confers non-small cell lung cancer patients with poor prognosis.

Authors: Qian Sun; Shuzhan Li; Yanan Wang; Haiyong Peng; Xiying Zhang; Yu Zheng; Chunjia Li; Li Li; Rongrong Chen; Xinxin Chen; Wenjing Bai; Xiangli Jiang; Liang Liu; Feng Wei; Boshi Wang; Yu Zhang; Hui Li; Xiubao Ren; Hongbing Zhang
Journal: Cell Death Differ Date: 2018-01-23 Impact factor: 15.828

PGAMgnam style: a glycolytic switch controls biosynthesis.

Review 1. Regulation of tumor metabolism by post translational modifications on metabolic enzymes.

2. An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma.

3. Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.

4. Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion.

5. Phosphoglyceric acid mutase-1 contributes to oncogenic mTOR-mediated tumor growth and confers non-small cell lung cancer patients with poor prognosis.

Review 6. The Influence of Metabolism on Drug Response in Cancer.

7. The Design and Synthesis of N-Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors.

8. PGM5 is a promising biomarker and may predict the prognosis of colorectal cancer patients.