Literature DB >> 23152591

Proteasomal inhibition as a treatment strategy for Parkinson's disease: the impact of α-synuclein on Nurr1.

Michael J Devine1.   

Abstract

Entities:  

Year:  2012        PMID： 23152591      PMCID： PMC6794012          DOI： 10.1523/JNEUROSCI.4224-12.2012

Source DB:  PubMed          Journal:  J Neurosci        ISSN： 0270-6474            Impact factor:   6.167


× No keyword cloud information.
  10 in total

1.  Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors.

Authors:  B D Butts; H R Hudson; D A Linseman; S S Le; K R Ryan; R J Bouchard; K A Heidenreich
Journal:  Mol Cell Neurosci       Date:  2005-10       Impact factor: 4.314

2.  Nurr1 in Parkinson's disease and related disorders.

Authors:  Yaping Chu; Weidong Le; Katie Kompoliti; Joseph Jankovic; Elliott J Mufson; Jeffrey H Kordower
Journal:  J Comp Neurol       Date:  2006-01-20       Impact factor: 3.215

3.  Nurr1 transcriptionally regulates the expression of alpha-synuclein.

Authors:  Yan Xiang Yang; David S Latchman
Journal:  Neuroreport       Date:  2008-05-28       Impact factor: 1.837

Review 4.  Disruption of protein quality control in Parkinson's disease.

Authors:  Casey Cook; Caroline Stetler; Leonard Petrucelli
Journal:  Cold Spring Harb Perspect Med       Date:  2012-05       Impact factor: 6.915

5.  Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1.

Authors:  Xian Lin; Loukia Parisiadou; Carmelo Sgobio; Guoxiang Liu; Jia Yu; Lixin Sun; Hoon Shim; Xing-Long Gu; Jing Luo; Cai-Xia Long; Jinhui Ding; Yolanda Mateo; Patricia H Sullivan; Ling-Gang Wu; David S Goldstein; David Lovinger; Huaibin Cai
Journal:  J Neurosci       Date:  2012-07-04       Impact factor: 6.167

6.  Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons.

Authors:  Banafsheh Kadkhodaei; Takehito Ito; Eliza Joodmardi; Bengt Mattsson; Claude Rouillard; Manolo Carta; Shin-ichi Muramatsu; Chiho Sumi-Ichinose; Takahide Nomura; Daniel Metzger; Pierre Chambon; Eva Lindqvist; Nils-Göran Larsson; Lars Olson; Anders Björklund; Hiroshi Ichinose; Thomas Perlmann
Journal:  J Neurosci       Date:  2009-12-16       Impact factor: 6.167

Review 7.  Genetic analysis of pathways to Parkinson disease.

Authors:  John Hardy
Journal:  Neuron       Date:  2010-10-21       Impact factor: 17.173

8.  Inhibition versus induction of apoptosis by proteasome inhibitors depends on concentration.

Authors:  K I Lin; J M Baraban; R R Ratan
Journal:  Cell Death Differ       Date:  1998-07       Impact factor: 15.828

9.  Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.

Authors:  Xian Lin; Loukia Parisiadou; Xing-Long Gu; Lizhen Wang; Hoon Shim; Lixin Sun; Chengsong Xie; Cai-Xia Long; Wan-Jou Yang; Jinhui Ding; Zsu Zsu Chen; Paul E Gallant; Jung-Hwa Tao-Cheng; Gay Rudow; Juan C Troncoso; Zhihua Liu; Zheng Li; Huaibin Cai
Journal:  Neuron       Date:  2009-12-24       Impact factor: 17.173

10.  Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.

Authors:  Lynn Bedford; David Hay; Anny Devoy; Simon Paine; Des G Powe; Rashmi Seth; Trevor Gray; Ian Topham; Kevin Fone; Nooshin Rezvani; Maureen Mee; Tim Soane; Robert Layfield; Paul W Sheppard; Ted Ebendal; Dmitry Usoskin; James Lowe; R John Mayer
Journal:  J Neurosci       Date:  2008-08-13       Impact factor: 6.167
  10 in total
  4 in total

Review 1.  Nurr1-Based Therapies for Parkinson's Disease.

Authors:  Jie Dong; Song Li; Jing-Lin Mo; Huai-Bin Cai; Wei-Dong Le
Journal:  CNS Neurosci Ther       Date:  2016-03-25       Impact factor: 5.243

2.  α-Synuclein Negatively Regulates Nurr1 Expression Through NF-κB-Related Mechanism.

Authors:  Congcong Jia; Hongqian Qi; Cheng Cheng; Xuefei Wu; Zhaofei Yang; Huaibin Cai; Sheng Chen; Weidong Le
Journal:  Front Mol Neurosci       Date:  2020-05-12       Impact factor: 5.639

3.  High Throughput Sequencing Identifies MicroRNAs Mediating α-Synuclein Toxicity by Targeting Neuroactive-Ligand Receptor Interaction Pathway in Early Stage of Drosophila Parkinson's Disease Model.

Authors:  Yan Kong; Xijun Liang; Lin Liu; Dongdong Zhang; Chao Wan; Zhenji Gan; Liudi Yuan
Journal:  PLoS One       Date:  2015-09-11       Impact factor: 3.240

4.  α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks.

Authors:  Ángel Juan García-Yagüe; Isabel Lastres-Becker; Leonidas Stefanis; Demetrios K Vassilatis; Antonio Cuadrado
Journal:  Mol Neurobiol       Date:  2021-10-05       Impact factor: 5.590
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.