Literature DB >> 23149024

A window into the invisible wound of war: functional neuroimaging of REM sleep in returning combat veterans with PTSD.

Anne Germain1, Jeffrey James, Salvatore Insana, Ryan J Herringa, Oommen Mammen, Julie Price, Eric Nofzinger.   

Abstract

Relative regional cerebral metabolic rate of glucose in rapid eye movement (REM) sleep and wakefulness was explored in combat veterans with and without posttraumatic stress disorder PTSD, using positron emission tomography. Hypermetabolism in brain regions involved in arousal regulation, fear responses, and reward processing persist during REM sleep in combat veterans with PTSD.
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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Year:  2012        PMID: 23149024      PMCID: PMC3570584          DOI: 10.1016/j.pscychresns.2012.05.007

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  7 in total

Review 1.  The neural basis of addiction: a pathology of motivation and choice.

Authors:  Peter W Kalivas; Nora D Volkow
Journal:  Am J Psychiatry       Date:  2005-08       Impact factor: 18.112

2.  Forebrain activation in REM sleep: an FDG PET study.

Authors:  E A Nofzinger; M A Mintun; M Wiseman; D J Kupfer; R Y Moore
Journal:  Brain Res       Date:  1997-10-03       Impact factor: 3.252

Review 3.  The development of a Clinician-Administered PTSD Scale.

Authors:  D D Blake; F W Weathers; L M Nagy; D G Kaloupek; F D Gusman; D S Charney; T M Keane
Journal:  J Trauma Stress       Date:  1995-01

4.  A method for the assessment of the functional neuroanatomy of human sleep using FDG PET.

Authors:  E A Nofzinger; M A Mintun; J Price; C C Meltzer; D Townsend; D J Buysse; C F Reynolds; M Dachille; J Matzzie; D J Kupfer; R Y Moore
Journal:  Brain Res Brain Res Protoc       Date:  1998-03

Review 5.  Sleep-specific mechanisms underlying posttraumatic stress disorder: integrative review and neurobiological hypotheses.

Authors:  Anne Germain; Daniel J Buysse; Eric Nofzinger
Journal:  Sleep Med Rev       Date:  2007-11-09       Impact factor: 11.609

6.  Where's the fun in that? Broadening the focus on reward function in depression.

Authors:  Erika E Forbes
Journal:  Biol Psychiatry       Date:  2009-08-01       Impact factor: 13.382

7.  REM sleep and the early development of posttraumatic stress disorder.

Authors:  Thomas A Mellman; Victoria Bustamante; Ana I Fins; Wilfred R Pigeon; Bruce Nolan
Journal:  Am J Psychiatry       Date:  2002-10       Impact factor: 18.112

  7 in total
  28 in total

1.  Evening-type military veterans report worse lifetime posttraumatic stress symptoms and greater brainstem activity across wakefulness and REM sleep.

Authors:  Brant P Hasler; Salvatore P Insana; Jeffrey A James; Anne Germain
Journal:  Biol Psychol       Date:  2013-07-02       Impact factor: 3.251

2.  The interaction of REM sleep with safety learning in humans: could a good night's sleep alter a traumatic experience?

Authors:  Rowan P Ogeil; Kathryn D Baker
Journal:  J Neurosci       Date:  2015-01-28       Impact factor: 6.167

3.  Effect of Experience and Psychophysiological Modification by Combat Stress in Soldier's Memory.

Authors:  Rosa Delgado-Moreno; Jose Juan Robles-Pérez; Susana Aznar-Laín; Vicente Javier Clemente-Suárez
Journal:  J Med Syst       Date:  2019-04-22       Impact factor: 4.460

4.  Effect of Combat Stress in the Psychophysiological Response of Elite and Non-Elite Soldiers.

Authors:  José Francisco Tornero-Aguilera; José Juan Robles-Pérez; Vicente Javier Clemente-Suárez
Journal:  J Med Syst       Date:  2017-05-15       Impact factor: 4.460

Review 5.  Sleep-dependent memory consolidation and its implications for psychiatry.

Authors:  Monique Goerke; Notger G Müller; Stefan Cohrs
Journal:  J Neural Transm (Vienna)       Date:  2015-10-30       Impact factor: 3.575

6.  Trauma associated sleep disorder: a proposed parasomnia encompassing disruptive nocturnal behaviors, nightmares, and REM without atonia in trauma survivors.

Authors:  Vincent Mysliwiec; Brian O'Reilly; Jason Polchinski; Herbert P Kwon; Anne Germain; Bernard J Roth
Journal:  J Clin Sleep Med       Date:  2014-10-15       Impact factor: 4.062

Review 7.  Sleep, Sleep Disorders, and Circadian Health following Mild Traumatic Brain Injury in Adults: Review and Research Agenda.

Authors:  Emerson M Wickwire; David M Schnyer; Anne Germain; Scott G Williams; Christopher J Lettieri; Ashlee B McKeon; Steven M Scharf; Ryan Stocker; Jennifer Albrecht; Neeraj Badjatia; Amy J Markowitz; Geoffrey T Manley
Journal:  J Neurotrauma       Date:  2018-08-24       Impact factor: 5.269

8.  The effect of continuous positive air pressure (CPAP) on nightmares in patients with posttraumatic stress disorder (PTSD) and obstructive sleep apnea (OSA).

Authors:  Sadeka Tamanna; Jefferson D Parker; Judith Lyons; M I Ullah
Journal:  J Clin Sleep Med       Date:  2014-06-15       Impact factor: 4.062

9.  Comparing neural correlates of REM sleep in posttraumatic stress disorder and depression: a neuroimaging study.

Authors:  Sommer Ebdlahad; Eric A Nofzinger; Jeffrey A James; Daniel J Buysse; Julie C Price; Anne Germain
Journal:  Psychiatry Res       Date:  2013-12-30       Impact factor: 3.222

10.  Circadian Contrasts in Heart Rate Variability Associated With Posttraumatic Stress Disorder Symptoms in a Young Adult Cohort.

Authors:  Michelle B Rissling; Paul A Dennis; Lana L Watkins; Patrick S Calhoun; Michelle F Dennis; Jean C Beckham; Junichiro Hayano; Christi S Ulmer
Journal:  J Trauma Stress       Date:  2016-09-07
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