| Literature DB >> 23148461 |
Kazutada Ikeuchi1, Shunsuke Ido, Satoshi Yoshimura, Tomohiro Asakawa, Makoto Inai, Yoshitaka Hamashima, Toshiyuki Kan.
Abstract
Asymmetric bromolactonization of prochiral cyclohexadiene derivatives with N-bromosuccimide proceeded in the presence of (DHQD)(2)PHAL as a chiral catalyst to afford the corresponding bromolactones with up to 93% ee. This reaction was also applicable to the kinetic resolution of a racemic cyclic ene-carboxylic acid, where the starting material was recovered with high enantioselectivity.Entities:
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Year: 2012 PMID： 23148461 DOI： 10.1021/ol302908a
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005