Literature DB >> 23148399

A sticky situation: methaemaglobinaemia in a hand trauma patient.

Yezen Sheena1, Emma Louise Baston, Andrew Downs, Darren L Chester.   

Abstract

We describe a case of methaemoglobinaemia (MtHb) in a previously healthy 39-year-old gentleman who presented with a traumatic glass laceration to his right wrist that required emergency surgery to control bleeding and repair his ulnar artery. The MtHb was noted on blood gas analysis by the anaesthetist after the patient had a drop in arterial oxygen saturation under general anaesthetic. We initially suspected the lidocaine local anaesthetic injected proximal to his wound for pain control in the emergency department an hour preoperatively, but then discovered that the patient was a recreational user of 'poppers' and had in fact been using these drugs just before his injury and hospitalisation. The patient's condition stabilised overnight with conservative management. Given how commonly hand surgeons and other clinical staff use local anaesthetics, we reviewed the literature on this uncommon, but potentially fatal, complication, its causes and evidence-based management.

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Year:  2012        PMID: 23148399      PMCID: PMC4544009          DOI: 10.1136/bcr-2012-007196

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

1.  Severe methemoglobinemia on reexposure to benzocaine.

Authors:  C Udeh; J Bittikofer; S T Sum-Ping
Journal:  J Clin Anesth       Date:  2001-03       Impact factor: 9.452

2.  Acquired methemoglobinemia. A case report.

Authors:  J W Foxworth; J A Roberts; S F Mahmoud
Journal:  Mo Med       Date:  1987-04

Review 3.  Methemoglobinemia: etiology, pharmacology, and clinical management.

Authors:  R O Wright; W J Lewander; A D Woolf
Journal:  Ann Emerg Med       Date:  1999-11       Impact factor: 5.721

4.  Symptomatic-low grade methemoglobinemia because of dapsone: a multiple hit hypothesis.

Authors:  Anna Skold; Robin Klein
Journal:  Am J Ther       Date:  2013 Nov-Dec       Impact factor: 2.688

Review 5.  Methaemoglobinaemia associated with the use of cocaine and volatile nitrites as recreational drugs: a review.

Authors:  Laura Hunter; Laura Gordge; Paul I Dargan; David M Wood
Journal:  Br J Clin Pharmacol       Date:  2011-07       Impact factor: 4.335

Review 6.  Severe methemoglobinemia complicating topical benzocaine use during endoscopy in a toddler: a case report and review of the literature.

Authors:  Ahmed Dahshan; G Kevin Donovan
Journal:  Pediatrics       Date:  2006-04       Impact factor: 7.124

7.  Methemoglobinemia related to local anesthetics: a summary of 242 episodes.

Authors:  Joanne Guay
Journal:  Anesth Analg       Date:  2009-03       Impact factor: 5.108

Review 8.  Concise review: methemoglobinemia.

Authors:  A Mansouri; A A Lurie
Journal:  Am J Hematol       Date:  1993-01       Impact factor: 10.047

Review 9.  Methemoglobin pathophysiology.

Authors:  E R Jaffé
Journal:  Prog Clin Biol Res       Date:  1981

10.  Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report.

Authors:  Sophie Kwok; Jacqueline L Fischer; John D Rogers
Journal:  J Med Case Rep       Date:  2008-01-23
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  2 in total

Review 1.  Lessons of the month 3: Intravenous poppers abuse: case report, management and possible complications.

Authors:  Alexander Reisinger; Susanne Vogt; Anna Essl; Ines Rauch; Florian Bangerl; Philipp Eller; Gerald Hackl
Journal:  Clin Med (Lond)       Date:  2020-03       Impact factor: 2.659

2.  Dapsone-induced methemoglobinemia: "Saturation gap"-The key to diagnosis.

Authors:  Shivinder Singh; Navdeep Sethi; Sushmitha Pandith; Gouri Shankar Ramesh
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2014-01
  2 in total

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