Literature DB >> 2314830

Establishment and characterization of a human ovarian serous cystadenocarcinoma cell line that produces the tumor markers CA-125 and tissue polypeptide antigen.

S Imai1, Y Kiyozuka, H Maeda, T Noda, H L Hosick.   

Abstract

A cultured cell line (SHIN-3) derived from a human ovarian serous cystadenocarcinoma which consistently produces two tumor markers, CA-125 and tissue polypeptide antigen (TPA) was established. After 1 week of culture of 1 x 10(5) cells, high levels of tumor marker were observed (the total CA-125 release was 1,500 U and the total TPA release was 37.5 U). Expression of CA-125 and TPA was also demonstrated in cultured cells immunohistochemically. The volume of CA-125 release per cell was highest just before the start of the logarithmic growth phase. TPA production was increased in the logarithmic growth phase, but its relationship to the total number of cells was not clear.

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Year:  1990        PMID： 2314830     DOI： 10.1159/000226813

Source DB:  PubMed          Journal:  Oncology        ISSN： 0030-2414            Impact factor:   2.935


  23 in total

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Journal:  Eur J Nucl Med       Date:  1996-05

2.  Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe.

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Journal:  Sci Transl Med       Date:  2011-11-23       Impact factor: 17.956

3.  Near infrared fluorescence-guided real-time endoscopic detection of peritoneal ovarian cancer nodules using intravenously injected indocyanine green.

Authors:  Nobuyuki Kosaka; Makoto Mitsunaga; Michelle R Longmire; Peter L Choyke; Hisataka Kobayashi
Journal:  Int J Cancer       Date:  2011-06-18       Impact factor: 7.396

4.  A comparison of the emission efficiency of four common green fluorescence dyes after internalization into cancer cells.

Authors:  Yukihiro Hama; Yasuteru Urano; Yoshinori Koyama; Marcelino Bernardo; Peter L Choyke; Hisataka Kobayashi
Journal:  Bioconjug Chem       Date:  2006 Nov-Dec       Impact factor: 4.774

5.  In vivo stable tumor-specific painting in various colors using dehalogenase-based protein-tag fluorescent ligands.

Authors:  Nobuyuki Kosaka; Mikako Ogawa; Peter L Choyke; Natasha Karassina; Cesear Corona; Mark McDougall; David T Lynch; Clifford C Hoyt; Richard M Levenson; Georgyi V Los; Hisataka Kobayashi
Journal:  Bioconjug Chem       Date:  2009-07       Impact factor: 4.774

6.  In search of specific cytotoxic T lymphocytes infiltrating or accompanying human ovarian carcinoma.

Authors:  M Apiranthitou-Drogari; C Paganin; S Bernasconi; G Losa; A Maneo; N Colombo; A Mantovani; P Allavena
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968

7.  Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases.

Authors:  Mikako Ogawa; Nobuyuki Kosaka; Michelle R Longmire; Yasuteru Urano; Peter L Choyke; Hisataka Kobayashi
Journal:  Mol Pharm       Date:  2009 Mar-Apr       Impact factor: 4.939

8.  Determination of optimal rhodamine fluorophore for in vivo optical imaging.

Authors:  Michelle R Longmire; Mikako Ogawa; Yukihiro Hama; Nobuyuki Kosaka; Celeste A S Regino; Peter L Choyke; Hisataka Kobayashi
Journal:  Bioconjug Chem       Date:  2008-07-09       Impact factor: 4.774

9.  Targeted optical fluorescence imaging of human ovarian adenocarcinoma using a galactosyl serum albumin-conjugated fluorophore.

Authors:  Andrew J Gunn; Yukihiro Hama; Yoshinori Koyama; Elise C Kohn; Peter L Choyke; Hisataka Kobayashi
Journal:  Cancer Sci       Date:  2007-09-02       Impact factor: 6.716

10.  GEP oncogene promotes cell proliferation through YAP activation in ovarian cancer.

Authors:  H Yagi; K Asanoma; T Ohgami; A Ichinoe; K Sonoda; K Kato
Journal:  Oncogene       Date:  2016-01-25       Impact factor: 9.867
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