Evidence for statin therapy in polycystic ovary syndrome.

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group that is associated with increased cardiovascular risk. In addition to its lipid-lowering effects, statin therapy has shown been shown to have beneficial pleiotropic effects that may contribute to their reduction in cardiovascular morbidity and mortality. In this review, the effect of statins on PCOS is discussed with reference to the underlying potential mechanism of action.