Literature DB >> 23148054

Reducing all-cause mortality among patients with psychiatric disorders: a population-based study.

Steve Kisely1, Neil Preston, Jianguo Xiao, David Lawrence, Sandra Louise, Elizabeth Crowe.   

Abstract

BACKGROUND: Among patients with psychiatric disorders, there are 10 times as many preventable deaths from physical disorders as there are from suicide. We investigated whether compulsory community treatment, such as community treatment orders, could reduce all-cause mortality among patients with psychiatric disorders.
METHODS: We conducted a population-based survival analysis of an inception cohort using record linking. The study period extended from November 1997 to December 2008. The cohort included patients from all community-based and inpatient psychiatric services in Western Australia (state population 1.8 million). We used a 2-stage design of matching and Cox regression to adjust for demographic characteristics, previous use of health services, diagnosis and length of psychiatric history. We collected data on successive cohorts for each year for which community treatment orders were used to measure changes in numbers of patients, their characteristics and outcomes. Our primary outcome was 2-year all-cause mortality. Our secondary outcomes were 1-and 3-year all-cause mortality.
RESULTS: The study population included 2958 patients with community treatment orders (cases) and 2958 matched controls (i.e., patients with psychiatric disorders who had not received a community treatment order). The average age for cases and controls was 36.7 years, and 63.7% (3771) of participants were men. Schizophrenia and other nonaffective psychoses were the most common diagnoses (73.4%) among participants. A total of 492 patients (8.3%) died during the study. Cox regression showed that, compared with controls, patients with community treatment orders had significantly lower all-cause mortality at 1, 2 and 3 years, with an adjusted hazard ratio of 0.62 (95% confidence interval 0.45-0.86) at 2 years. The greatest effect was on death from physical illnesses such as cancer, cardiovascular disease or diseases of the central nervous system. This association disappeared when we adjusted for increased outpatient and community contacts with psychiatric services.
INTERPRETATION: Community treatment orders might reduce mortality among patients with psychiatric disorders. This may be partly explained by increased contact with health services in the community. However, the effects of uncontrolled confounders cannot be excluded.

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Mesh:

Year:  2012        PMID: 23148054      PMCID: PMC3537812          DOI: 10.1503/cmaj.121077

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  22 in total

1.  Factors influencing compulsory admission of psychiatric patients.

Authors:  A Riecher; W Rössler; W Löffler; B Fätkenheuer
Journal:  Psychol Med       Date:  1991-02       Impact factor: 7.723

2.  Strategies for preventing suicide.

Authors:  G Lewis; K Hawton; P Jones
Journal:  Br J Psychiatry       Date:  1997-10       Impact factor: 9.319

3.  Assessing the New York City involuntary outpatient commitment pilot program.

Authors:  H J Steadman; K Gounis; D Dennis; K Hopper; B Roche; M Swartz; P C Robbins
Journal:  Psychiatr Serv       Date:  2001-03       Impact factor: 3.084

4.  Mental health care for Asian, black and white patients with non-affective psychoses: pathways to the psychiatric hospital, in-patient and after-care.

Authors:  M J Commander; R Cochrane; S P Sashidharan; F Akilu; E Wildsmith
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  1999-09       Impact factor: 4.328

5.  Can involuntary outpatient commitment reduce hospital recidivism?: Findings from a randomized trial with severely mentally ill individuals.

Authors:  M S Swartz; J W Swanson; H R Wagner; B J Burns; V A Hiday; R Borum
Journal:  Am J Psychiatry       Date:  1999-12       Impact factor: 18.112

6.  beta Blockade after myocardial infarction: systematic review and meta regression analysis.

Authors:  N Freemantle; J Cleland; P Young; J Mason; J Harrison
Journal:  BMJ       Date:  1999-06-26

7.  Quality of medical care and excess mortality in older patients with mental disorders.

Authors:  B G Druss; W D Bradford; R A Rosenheck; M J Radford; H M Krumholz
Journal:  Arch Gen Psychiatry       Date:  2001-06

Review 8.  Compulsory community and involuntary outpatient treatment for people with severe mental disorders.

Authors:  Steve R Kisely; Leslie Anne Campbell; Neil J Preston
Journal:  Cochrane Database Syst Rev       Date:  2011-02-16

9.  Assessing the outcome of compulsory psychiatric treatment in the community: epidemiological study in Western Australia.

Authors:  Neil J Preston; Steve Kisely; Jianguo Xiao
Journal:  BMJ       Date:  2002-05-25

10.  Community treatment orders: relationship to clinical care, medication compliance, behavioural disturbance and readmission.

Authors:  K Vaughan; N McConaghy; C Wolf; C Myhr; T Black
Journal:  Aust N Z J Psychiatry       Date:  2000-10       Impact factor: 5.744

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  17 in total

1.  Residence Conditions on Community Treatment Orders.

Authors:  John Dawson; Richard O'Reilly
Journal:  Can J Psychiatry       Date:  2015-11       Impact factor: 4.356

2.  The utility of outpatient commitment: acute medical care access and protecting health.

Authors:  Steven P Segal; Stephania L Hayes; Lachlan Rimes
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2018-04-06       Impact factor: 4.328

3.  Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder.

Authors:  Christoph U Correll; Johan Detraux; Jan De Lepeleire; Marc De Hert
Journal:  World Psychiatry       Date:  2015-06       Impact factor: 49.548

4.  Community Treatment Orders and Other Forms of Mandatory Outpatient Treatment.

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Journal:  Can J Psychiatry       Date:  2019-05       Impact factor: 4.356

5.  Is the effect of compulsory community treatment on preventable deaths from physical disorders mediated by better access to specialized medical procedures?

Authors:  Steve Kisely; Jianguo Xiao; David Lawrence; Le Jian
Journal:  Can J Psychiatry       Date:  2014-01       Impact factor: 4.356

Review 6.  Effectiveness of Community Treatment Orders: The International Evidence.

Authors:  Jorun Rugkåsa
Journal:  Can J Psychiatry       Date:  2016-01-01       Impact factor: 4.356

7.  The utility of outpatient commitment: Reduced-risks of victimization and crime perpetration.

Authors:  Steven P Segal; Lachlan Rimes; Stephania L Hayes
Journal:  Eur Psychiatry       Date:  2019-01-14       Impact factor: 5.361

8.  Risk of suicide after a concussion.

Authors:  Michael Fralick; Deva Thiruchelvam; Homer C Tien; Donald A Redelmeier
Journal:  CMAJ       Date:  2016-02-08       Impact factor: 8.262

9.  The Utility of Outpatient Commitment: II. Mortality Risk and Protecting Health, Safety, and Quality of Life.

Authors:  Steven P Segal; Stephania L Hayes; Lachlan Rimes
Journal:  Psychiatr Serv       Date:  2017-08-01       Impact factor: 3.084

Review 10.  Compulsory community and involuntary outpatient treatment for people with severe mental disorders.

Authors:  Steve R Kisely; Leslie A Campbell; Richard O'Reilly
Journal:  Cochrane Database Syst Rev       Date:  2017-03-17
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