OBJECTIVE: Evaluate the need for urine culture in early neonatal sepsis workup of term and late preterm infants. STUDY DESIGN: Urine culture by suprapubic aspiration or catheter was included in early sepsis evaluations of 173 term and late preterm newborns (mean gestational age 38.6 ± 2.0 weeks) during a 6-month study period. A historic control group included 182 newborns (38.6 ± 2.9 weeks) who had sepsis evaluations without routine urine cultures a year earlier. RESULTS: Urine cultures were sampled in 106 (61%) of the study group, No significant differences were found between study and control groups in the rate of bacteremia (1.73% versus 2.2%) or urinary tract infection (UTI; 0.94% versus 1.1%), which was low. Early UTIs were not accompanied by bacteremia or structural anomalies and were associated with exacerbation of neonatal jaundice in two of three infants. CONCLUSIONS: There seems to be no justification for routine urine culture in early neonatal sepsis workup of term and late preterm infants, unless there are accompanying clinical symptoms, usually related to neonatal jaundice. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
OBJECTIVE: Evaluate the need for urine culture in early neonatal sepsis workup of term and late preterm infants. STUDY DESIGN: Urine culture by suprapubic aspiration or catheter was included in early sepsis evaluations of 173 term and late preterm newborns (mean gestational age 38.6 ± 2.0 weeks) during a 6-month study period. A historic control group included 182 newborns (38.6 ± 2.9 weeks) who had sepsis evaluations without routine urine cultures a year earlier. RESULTS: Urine cultures were sampled in 106 (61%) of the study group, No significant differences were found between study and control groups in the rate of bacteremia (1.73% versus 2.2%) or urinary tract infection (UTI; 0.94% versus 1.1%), which was low. Early UTIs were not accompanied by bacteremia or structural anomalies and were associated with exacerbation of neonatal jaundice in two of three infants. CONCLUSIONS: There seems to be no justification for routine urine culture in early neonatal sepsis workup of term and late preterm infants, unless there are accompanying clinical symptoms, usually related to neonatal jaundice. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Authors: Alexander B Mohseny; Veerle van Velze; Sylke J Steggerda; Vivianne E H J Smits-Wintjens; Vincent Bekker; Enrico Lopriore Journal: Eur J Pediatr Date: 2017-10-23 Impact factor: 3.183
Authors: Joern-Hendrik Weitkamp; Judy L Aschner; Wallly A Carlo; Eduardo Bancalari; Jose A Perez; Cristina T Navarrete; Robert L Schelonka; M Whit Walker; Peter Porcelli; Thomas M O'Shea; Charles Palmer; Sarah Grossarth; Douglas E Lake; Karen D Fairchild Journal: Pediatr Res Date: 2019-12-04 Impact factor: 3.756
Authors: Joseph Y Ting; Julie Autmizguine; Michael S Dunn; Julie Choudhury; Julie Blackburn; Shikha Gupta-Bhatnagar; Katrin Assen; Julie Emberley; Sarah Khan; Jessica Leung; Grace J Lin; Destiny Lu-Cleary; Frances Morin; Lindsay L Richter; Isabelle Viel-Thériault; Ashley Roberts; Kyong-Soon Lee; Erik D Skarsgard; Joan Robinson; Prakesh S Shah Journal: Front Pediatr Date: 2022-07-08 Impact factor: 3.569