OBJECTIVE: To determine the frequency of peripheral arterial disease (PAD) in type 2 diabetic patients. STUDY DESIGN: Cross-sectional observational study. PLACE AND DURATION OF STUDY: Diabetes Clinic, Medical Unit III, Jinnah Postgraduate Medical Centre, Karachi, from January to June 2010. METHODOLOGY: Three hundred and eighty seven (387) type II diabetic patients of either gender and any age were included in the study. Patients with a previous history of trauma to the arterial vasculature, pregnancy and those who underwent arterial graft procedures were excluded. Non-purposive convenient sampling technique was used to enroll patients in the study. PAD was diagnosed when ankle-brachial index (ABI) was less than 0.9. A p-value of less than 0.05 was considered statistically significant. RESULTS: Out of 387 studied patients, 128 were males (33.1%) and 259 were females (66.9%). Mean age was 52.22 ± 9.671 (22 - 76) years in the entire cohort. Mean duration of diabetes was 9.38 ± 6.39 years. PAD was detected in 152 (39.28%) of the total study subjects. Thirty-one of 128 male patients (24.22%) had PAD disease while 121 out of 259 female patients (46.71%) had evidence of PAD (p = 0.001). Hypertension was a significantly associated factor (p = 0.002). CONCLUSION: A high frequency of PAD was observed in the diabetic population particularly with hypertension and more prevalent in females.
OBJECTIVE: To determine the frequency of peripheral arterial disease (PAD) in type 2 diabeticpatients. STUDY DESIGN: Cross-sectional observational study. PLACE AND DURATION OF STUDY: Diabetes Clinic, Medical Unit III, Jinnah Postgraduate Medical Centre, Karachi, from January to June 2010. METHODOLOGY: Three hundred and eighty seven (387) type II diabeticpatients of either gender and any age were included in the study. Patients with a previous history of trauma to the arterial vasculature, pregnancy and those who underwent arterial graft procedures were excluded. Non-purposive convenient sampling technique was used to enroll patients in the study. PAD was diagnosed when ankle-brachial index (ABI) was less than 0.9. A p-value of less than 0.05 was considered statistically significant. RESULTS: Out of 387 studied patients, 128 were males (33.1%) and 259 were females (66.9%). Mean age was 52.22 ± 9.671 (22 - 76) years in the entire cohort. Mean duration of diabetes was 9.38 ± 6.39 years. PAD was detected in 152 (39.28%) of the total study subjects. Thirty-one of 128 male patients (24.22%) had PAD disease while 121 out of 259 female patients (46.71%) had evidence of PAD (p = 0.001). Hypertension was a significantly associated factor (p = 0.002). CONCLUSION: A high frequency of PAD was observed in the diabetic population particularly with hypertension and more prevalent in females.
Authors: Shair Zaman Khan; Nazish Waris; Zahid Miyan; Muhammad Saif Ulhaque; Asher Fawwad Journal: Pak J Med Sci Date: 2019 Jul-Aug Impact factor: 1.088
Authors: Sadaf Kamil; Thomas S G Sehested; Nicholas Carlson; Kim Houlind; Jens F Lassen; Casper N Bang; Helena Dominguez; Christian T Pedersen; Gunnar H Gislason Journal: BMC Cardiovasc Disord Date: 2019-10-24 Impact factor: 2.298