Literature DB >> 23146223

Evaluation of core-shell particle columns for ion-pair reversed-phase liquid chromatography analysis of oligonucleotides.

Mirlinda Biba1, Christopher J Welch, Joe P Foley, Bing Mao, Enrique Vazquez, Rebecca A Arvary.   

Abstract

An investigation into the use of core-shell particle columns for separation of short (∼21 base pairs) RNA oligonucleotides by ion-pair reversed-phase liquid chromatography (IP-RPLC) showed improved resolution for a number of test analytes relative to conventional (fully-porous) reversed-phase columns. The best resolutions were obtained using columns packed with smaller sub-2μm core-shell particles.
Copyright © 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID： 23146223     DOI： 10.1016/j.jpba.2012.09.007

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN： 0731-7085            Impact factor:   3.935


  3 in total

1.  A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications.

Authors:  Weiling Maggie Cai; Yok Hian Chionh; Fabian Hia; Chen Gu; Stefanie Kellner; Megan E McBee; Chee Sheng Ng; Yan Ling Joy Pang; Erin G Prestwich; Kok Seong Lim; I Ramesh Babu; Thomas J Begley; Peter C Dedon
Journal:  Methods Enzymol       Date:  2015-07-17       Impact factor: 1.600

Review 2.  Oligonucleotides Isolation and Separation-A Review on Adsorbent Selection.

Authors:  Sylwia Studzińska; Łukasz Nuckowski; Bogusław Buszewski
Journal:  Int J Mol Sci       Date:  2022-08-23       Impact factor: 6.208

3.  Nucleic acid separations using superficially porous silica particles.

Authors:  Elizabeth D Close; Alison O Nwokeoji; Dafydd Milton; Ken Cook; Darsha M Hindocha; Elliot C Hook; Helen Wood; Mark J Dickman
Journal:  J Chromatogr A       Date:  2016-02-23       Impact factor: 4.759
  3 in total

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