| Literature DB >> 2314601 |
R S Fisher1, B J Cysyk, R P Lesser, M J Pontecorvo, J T Ferkany, P R Schwerdt, J Hart, B Gordon.
Abstract
We performed a double-blind, crossover, add-on study of the antitussive agent dextromethorphan (DM 120 mg/d) as therapy for seizures on 9 patients suffering from severe complex partial seizures. DM had no significant influence on key laboratory values, nor on anticonvulsant drug levels. Side effects were negligible. Complex partial seizure frequency increased 25% during the DM arm of the study, although this increase was not clinically significant.Entities:
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Year: 1990 PMID： 2314601 DOI： 10.1212/wnl.40.3_part_1.547
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910